Computational based design and tracking of synthetic variants of Porcine circovirus reveal relations between silent genomic information and viral fitness

Abstract Viral genomes not only code the protein content, but also include silent, overlapping codes which are important to the regulation of the viral life cycle and affect its evolution. Due to the high density of these codes, their non-modular nature and the complex intracellular processes they e...

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Autores principales: Lia Baron, Shimshi Atar, Hadas Zur, Modi Roopin, Eli Goz, Tamir Tuller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e9a8f059b8c9470f84d002f5d313aabe
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