Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways

Nitrogen-starved fission yeast cells survive for weeks without dividing. Here, the authors show that some of these surviving cells accumulate mutations in the stress- and mitogen-activated protein kinase pathways and outcompete their parental cells, which provide nutrients for the mutant cells.

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Autores principales:	Rostyslav Makarenko, Claire Denis, Stefania Francesconi, Serge Gangloff, Benoît Arcangioli
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e9ad02e770e946138ceeb1a29db9280c
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spelling	oai:doaj.org-article:e9ad02e770e946138ceeb1a29db9280c2021-12-02T17:32:59ZNitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways10.1038/s41467-020-15880-y2041-1723https://doaj.org/article/e9ad02e770e946138ceeb1a29db9280c2020-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15880-yhttps://doaj.org/toc/2041-1723Nitrogen-starved fission yeast cells survive for weeks without dividing. Here, the authors show that some of these surviving cells accumulate mutations in the stress- and mitogen-activated protein kinase pathways and outcompete their parental cells, which provide nutrients for the mutant cells.Rostyslav MakarenkoClaire DenisStefania FrancesconiSerge GangloffBenoît ArcangioliNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rostyslav Makarenko Claire Denis Stefania Francesconi Serge Gangloff Benoît Arcangioli Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
description	Nitrogen-starved fission yeast cells survive for weeks without dividing. Here, the authors show that some of these surviving cells accumulate mutations in the stress- and mitogen-activated protein kinase pathways and outcompete their parental cells, which provide nutrients for the mutant cells.
format	article
author	Rostyslav Makarenko Claire Denis Stefania Francesconi Serge Gangloff Benoît Arcangioli
author_facet	Rostyslav Makarenko Claire Denis Stefania Francesconi Serge Gangloff Benoît Arcangioli
author_sort	Rostyslav Makarenko
title	Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
title_short	Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
title_full	Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
title_fullStr	Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
title_full_unstemmed	Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways
title_sort	nitrogen starvation reveals the mitotic potential of mutants in the s/mapk pathways
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e9ad02e770e946138ceeb1a29db9280c
work_keys_str_mv	AT rostyslavmakarenko nitrogenstarvationrevealsthemitoticpotentialofmutantsinthesmapkpathways AT clairedenis nitrogenstarvationrevealsthemitoticpotentialofmutantsinthesmapkpathways AT stefaniafrancesconi nitrogenstarvationrevealsthemitoticpotentialofmutantsinthesmapkpathways AT sergegangloff nitrogenstarvationrevealsthemitoticpotentialofmutantsinthesmapkpathways AT benoitarcangioli nitrogenstarvationrevealsthemitoticpotentialofmutantsinthesmapkpathways
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Nitrogen starvation reveals the mitotic potential of mutants in the S/MAPK pathways

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