Synaptic FUS accumulation triggers early misregulation of synaptic RNAs in a mouse model of ALS
Mutations in the RNA-binding protein FUS contribute to ALS. Here the authors use CLIP-seq on synaptoneurosomes to identify proteins associated with synapse organization and plasticity that are differentially regulated in a knock-in ALS mouse model.
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Main Authors: | , , , , , , , , , , , |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/e9c043534e61495b8e1dfb249245ca1e |
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