Searching for a UV-filter in the eyes of high-flying birds

Abstract The eye lens is a unique organ as no cells can be replaced throughout life. This makes it decisive that the lens is protected against damaging UV-radiation. An ultraviolet (UV)-absorbing compound of unknown identity is present in the aqueous humor of geese (wild and domestic) and other bird...

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Autores principales: Malgorzata Zawadzka, Beatrix Ràcz, Dario Ambrosini, Carl Henrik Görbitz, Jens Preben Morth, Alistair L. Wilkins, Anja Østeby, Katja Benedikte Prestø Elgstøen, Elsa Lundanes, Frode Rise, Amund Ringvold, Steven Ray Wilson
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Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e9c06df47e0c48848f3c1bbdddfbde28
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spelling oai:doaj.org-article:e9c06df47e0c48848f3c1bbdddfbde282021-12-02T14:01:38ZSearching for a UV-filter in the eyes of high-flying birds10.1038/s41598-020-79533-22045-2322https://doaj.org/article/e9c06df47e0c48848f3c1bbdddfbde282021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-79533-2https://doaj.org/toc/2045-2322Abstract The eye lens is a unique organ as no cells can be replaced throughout life. This makes it decisive that the lens is protected against damaging UV-radiation. An ultraviolet (UV)-absorbing compound of unknown identity is present in the aqueous humor of geese (wild and domestic) and other birds flying at high altitudes. A goose aqueous humor extract, that was believed to contain the UV protective compound which was designated as “compound X”, was fractionated and examined using a variety of spectroscopic techniques including LC–MS and high field one- and two dimensional-NMR methods. A series of compounds were identified but none of them appeared to be the UV protective “compound X”. It may be that the level of the UV protective compound in goose aqueous humor is much less than the compounds identified in our investigation, or it may have been degraded by the isolation and chromatographic purification protocols used in our investigations.Malgorzata ZawadzkaBeatrix RàczDario AmbrosiniCarl Henrik GörbitzJens Preben MorthAlistair L. WilkinsAnja ØstebyKatja Benedikte Prestø ElgstøenElsa LundanesFrode RiseAmund RingvoldSteven Ray WilsonNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Malgorzata Zawadzka
Beatrix Ràcz
Dario Ambrosini
Carl Henrik Görbitz
Jens Preben Morth
Alistair L. Wilkins
Anja Østeby
Katja Benedikte Prestø Elgstøen
Elsa Lundanes
Frode Rise
Amund Ringvold
Steven Ray Wilson
Searching for a UV-filter in the eyes of high-flying birds
description Abstract The eye lens is a unique organ as no cells can be replaced throughout life. This makes it decisive that the lens is protected against damaging UV-radiation. An ultraviolet (UV)-absorbing compound of unknown identity is present in the aqueous humor of geese (wild and domestic) and other birds flying at high altitudes. A goose aqueous humor extract, that was believed to contain the UV protective compound which was designated as “compound X”, was fractionated and examined using a variety of spectroscopic techniques including LC–MS and high field one- and two dimensional-NMR methods. A series of compounds were identified but none of them appeared to be the UV protective “compound X”. It may be that the level of the UV protective compound in goose aqueous humor is much less than the compounds identified in our investigation, or it may have been degraded by the isolation and chromatographic purification protocols used in our investigations.
format article
author Malgorzata Zawadzka
Beatrix Ràcz
Dario Ambrosini
Carl Henrik Görbitz
Jens Preben Morth
Alistair L. Wilkins
Anja Østeby
Katja Benedikte Prestø Elgstøen
Elsa Lundanes
Frode Rise
Amund Ringvold
Steven Ray Wilson
author_facet Malgorzata Zawadzka
Beatrix Ràcz
Dario Ambrosini
Carl Henrik Görbitz
Jens Preben Morth
Alistair L. Wilkins
Anja Østeby
Katja Benedikte Prestø Elgstøen
Elsa Lundanes
Frode Rise
Amund Ringvold
Steven Ray Wilson
author_sort Malgorzata Zawadzka
title Searching for a UV-filter in the eyes of high-flying birds
title_short Searching for a UV-filter in the eyes of high-flying birds
title_full Searching for a UV-filter in the eyes of high-flying birds
title_fullStr Searching for a UV-filter in the eyes of high-flying birds
title_full_unstemmed Searching for a UV-filter in the eyes of high-flying birds
title_sort searching for a uv-filter in the eyes of high-flying birds
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/e9c06df47e0c48848f3c1bbdddfbde28
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