RNA binding of Hfq monomers promotes RelA-mediated hexamerization in a limiting Hfq environment

RelA stimulates RyhB small RNA–target mRNA interaction by promoting assembly of Hfq monomers into hexamers. Here the authors show that RelA-mediated Hfq hexamerization requires an initial binding of RNA to Hfq monomers.

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Autores principales: Pallabi Basu, Maya Elgrably-Weiss, Fouad Hassouna, Manoj Kumar, Reuven Wiener, Shoshy Altuvia
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/e9c5197e01e44b3fab2266c9e1eaaceb
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