Invasion of vaginal epithelial cells by uropathogenic Escherichia coli

Uropathogenic E. coli can adhere to vaginal epithelial cells preceding urinary tract infection (UTI). Here, Brannon et al. show that urinary E. coli isolates can not only adhere to, but also invade vaginal cells in mouse UTI models and in clinical samples obtained from women with recurrent UTI.

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Autores principales:	John R. Brannon, Taryn L. Dunigan, Connor J. Beebout, Tamia Ross, Michelle A. Wiebe, William S. Reynolds, Maria Hadjifrangiskou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/e9c88d725ec94a6a8c8225daaf607b56
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spelling	oai:doaj.org-article:e9c88d725ec94a6a8c8225daaf607b562021-12-02T18:24:49ZInvasion of vaginal epithelial cells by uropathogenic Escherichia coli10.1038/s41467-020-16627-52041-1723https://doaj.org/article/e9c88d725ec94a6a8c8225daaf607b562020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16627-5https://doaj.org/toc/2041-1723Uropathogenic E. coli can adhere to vaginal epithelial cells preceding urinary tract infection (UTI). Here, Brannon et al. show that urinary E. coli isolates can not only adhere to, but also invade vaginal cells in mouse UTI models and in clinical samples obtained from women with recurrent UTI.John R. BrannonTaryn L. DuniganConnor J. BeeboutTamia RossMichelle A. WiebeWilliam S. ReynoldsMaria HadjifrangiskouNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q John R. Brannon Taryn L. Dunigan Connor J. Beebout Tamia Ross Michelle A. Wiebe William S. Reynolds Maria Hadjifrangiskou Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
description	Uropathogenic E. coli can adhere to vaginal epithelial cells preceding urinary tract infection (UTI). Here, Brannon et al. show that urinary E. coli isolates can not only adhere to, but also invade vaginal cells in mouse UTI models and in clinical samples obtained from women with recurrent UTI.
format	article
author	John R. Brannon Taryn L. Dunigan Connor J. Beebout Tamia Ross Michelle A. Wiebe William S. Reynolds Maria Hadjifrangiskou
author_facet	John R. Brannon Taryn L. Dunigan Connor J. Beebout Tamia Ross Michelle A. Wiebe William S. Reynolds Maria Hadjifrangiskou
author_sort	John R. Brannon
title	Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
title_short	Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
title_full	Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
title_fullStr	Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
title_full_unstemmed	Invasion of vaginal epithelial cells by uropathogenic Escherichia coli
title_sort	invasion of vaginal epithelial cells by uropathogenic escherichia coli
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/e9c88d725ec94a6a8c8225daaf607b56
work_keys_str_mv	AT johnrbrannon invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT tarynldunigan invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT connorjbeebout invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT tamiaross invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT michelleawiebe invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT williamsreynolds invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli AT mariahadjifrangiskou invasionofvaginalepithelialcellsbyuropathogenicescherichiacoli
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Invasion of vaginal epithelial cells by uropathogenic Escherichia coli

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