Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort
Rational design in metabolic engineering is often difficult and limited to small screens, favouring construction of compressed smart libraries. Here the authors introduce RedLibs, an algorithm to design combinatorial RBS libraries to allow pathway optimization with minimal experimental resources.
Guardado en:
Autores principales: | Markus Jeschek, Daniel Gerngross, Sven Panke |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/e9c8e8a8f07c4ecbac79a4d985f6ac3a |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
COMPASS for rapid combinatorial optimization of biochemical pathways based on artificial transcription factors
por: Gita Naseri, et al.
Publicado: (2019) -
Chemo-enzymatic cascades to produce cycloalkenes from bio-based resources
por: Shuke Wu, et al.
Publicado: (2019) -
Special issue on: robust combinatorial optimization
por: Arie M.C.A. Koster, et al.
Publicado: (2018) -
Comprehensive assessment of TP53 loss of function using multiple combinatorial mutagenesis libraries
por: Vincent Carbonnier, et al.
Publicado: (2020) -
Multiplexed characterization of rationally designed promoter architectures deconstructs combinatorial logic for IPTG-inducible systems
por: Timothy C. Yu, et al.
Publicado: (2021)