Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort

Rational design in metabolic engineering is often difficult and limited to small screens, favouring construction of compressed smart libraries. Here the authors introduce RedLibs, an algorithm to design combinatorial RBS libraries to allow pathway optimization with minimal experimental resources.

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Detalles Bibliográficos
Autores principales: Markus Jeschek, Daniel Gerngross, Sven Panke
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
Materias:
Q
Acceso en línea:https://doaj.org/article/e9c8e8a8f07c4ecbac79a4d985f6ac3a
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