A Mouse Model for <italic toggle="yes">Betacoronavirus</italic> Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

A Mouse Model for <italic toggle="yes">Betacoronavirus</italic> Subgroup 2c Using a Bat Coronavirus Strain HKU5 Variant

ABSTRACT Cross-species transmission of zoonotic coronaviruses (CoVs) can result in pandemic disease outbreaks. Middle East respiratory syndrome CoV (MERS-CoV), identified in 2012, has caused 182 cases to date, with ~43% mortality, and no small animal model has been reported. MERS-CoV and Pipistrellu...

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Bibliographic Details
Main Authors: Sudhakar Agnihothram, Boyd L. Yount, Eric F. Donaldson, Jeremy Huynh, Vineet D. Menachery, Lisa E. Gralinski, Rachel L. Graham, Michelle M. Becker, Sakshi Tomar, Trevor D. Scobey, Heather L. Osswald, Alan Whitmore, Robin Gopal, Arun K. Ghosh, Andrew Mesecar, Maria Zambon, Mark Heise, Mark R. Denison, Ralph S. Baric
Format: article
Language:EN
Published: American Society for Microbiology 2014
Subjects:
Microbiology
QR1-502
Online Access:https://doaj.org/article/e9cfa1a0b1b145eba9f257143e0e07a0
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