Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application

Parameters of oxygen electroreduction on glassy carbon electrode modified with multi-walled carbon nanotubes were found. Increase in the oxygen reduction currents and system reversibility was observed compared to unmodified electrode, which allows to use cyclic voltammetry for investigation of react...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ziyatdinova G.K., Zakharova S.P., Budnikov H.C.
Formato:	article
Lenguaje:	EN RU
Publicado:	Kazan Federal University 2015
Materias:	voltammetry chemically modified electrodes superoxide anion radical phenolic antioxidants antioxidant capacity medicinal herbs Science Q
Acceso en línea:	https://doaj.org/article/e9d01bb812a14934b610a0ef2cdc9b38
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:e9d01bb812a14934b610a0ef2cdc9b38
record_format	dspace
spelling	oai:doaj.org-article:e9d01bb812a14934b610a0ef2cdc9b382021-12-02T19:17:28ZReactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application1815-61692500-218Xhttps://doaj.org/article/e9d01bb812a14934b610a0ef2cdc9b382015-06-01T00:00:00Zhttp://kpfu.ru/portal/docs/F293363080/157_2_est_11_e.pdfhttps://doaj.org/toc/1815-6169https://doaj.org/toc/2500-218XParameters of oxygen electroreduction on glassy carbon electrode modified with multi-walled carbon nanotubes were found. Increase in the oxygen reduction currents and system reversibility was observed compared to unmodified electrode, which allows to use cyclic voltammetry for investigation of reactions of electrogenerated superoxide anion radical with antioxidants. It was revealed that phenolic antioxidants act as proton donors (i.e., as Brønsted acids) and their interaction with superoxide anion radical follows ECE mechanism. The rate constants for reactions of 19 phenolic antioxidants with superoxide anion radical were calculated. The values of these constants were relatively similar, varied in the range of 6.8·104 ÷ 11.0·104 L/mol·s, and thereby reflected the slight influence of the structure of phenolic antioxidants, in particular the number and position of hydroxyl groups, as well as the steric effects of substituents. A volt-ammetric method was developed for evaluation of the superoxide scavenging capacity based on the relative increase in oxygen reduction current in the presence of antioxidants. The approach was tested on 11 samples of medicinal herb tinctures. The superoxide scavenging capacity was expressed in gallic acid equiva-lents per 1 mL of tincture. Positive correlation of the superoxide scavenging capacity with antioxidant activity (r = 0.7083 at rcrit = 0.602) was obtained.Ziyatdinova G.K.Zakharova S.P.Budnikov H.C.Kazan Federal Universityarticlevoltammetrychemically modified electrodessuperoxide anion radicalphenolic antioxidantsantioxidant capacitymedicinal herbsScienceQENRUUčënye Zapiski Kazanskogo Universiteta. Seriâ Estestvennye Nauki, Vol 157, Iss 2, Pp 129-142 (2015)
institution	DOAJ
collection	DOAJ
language	EN RU
topic	voltammetry chemically modified electrodes superoxide anion radical phenolic antioxidants antioxidant capacity medicinal herbs Science Q
spellingShingle	voltammetry chemically modified electrodes superoxide anion radical phenolic antioxidants antioxidant capacity medicinal herbs Science Q Ziyatdinova G.K. Zakharova S.P. Budnikov H.C. Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
description	Parameters of oxygen electroreduction on glassy carbon electrode modified with multi-walled carbon nanotubes were found. Increase in the oxygen reduction currents and system reversibility was observed compared to unmodified electrode, which allows to use cyclic voltammetry for investigation of reactions of electrogenerated superoxide anion radical with antioxidants. It was revealed that phenolic antioxidants act as proton donors (i.e., as Brønsted acids) and their interaction with superoxide anion radical follows ECE mechanism. The rate constants for reactions of 19 phenolic antioxidants with superoxide anion radical were calculated. The values of these constants were relatively similar, varied in the range of 6.8·104 ÷ 11.0·104 L/mol·s, and thereby reflected the slight influence of the structure of phenolic antioxidants, in particular the number and position of hydroxyl groups, as well as the steric effects of substituents. A volt-ammetric method was developed for evaluation of the superoxide scavenging capacity based on the relative increase in oxygen reduction current in the presence of antioxidants. The approach was tested on 11 samples of medicinal herb tinctures. The superoxide scavenging capacity was expressed in gallic acid equiva-lents per 1 mL of tincture. Positive correlation of the superoxide scavenging capacity with antioxidant activity (r = 0.7083 at rcrit = 0.602) was obtained.
format	article
author	Ziyatdinova G.K. Zakharova S.P. Budnikov H.C.
author_facet	Ziyatdinova G.K. Zakharova S.P. Budnikov H.C.
author_sort	Ziyatdinova G.K.
title	Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
title_short	Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
title_full	Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
title_fullStr	Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
title_full_unstemmed	Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application
title_sort	reactions of phenolic antioxidants with electrogenerated superoxide anion radical and their analytical application
publisher	Kazan Federal University
publishDate	2015
url	https://doaj.org/article/e9d01bb812a14934b610a0ef2cdc9b38
work_keys_str_mv	AT ziyatdinovagk reactionsofphenolicantioxidantswithelectrogeneratedsuperoxideanionradicalandtheiranalyticalapplication AT zakharovasp reactionsofphenolicantioxidantswithelectrogeneratedsuperoxideanionradicalandtheiranalyticalapplication AT budnikovhc reactionsofphenolicantioxidantswithelectrogeneratedsuperoxideanionradicalandtheiranalyticalapplication
_version_	1718376945401462784

Reactions of Phenolic Antioxidants with Electrogenerated Superoxide Anion Radical and Their Analytical Application

Ejemplares similares