Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis

Abstract We aimed to investigate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in evaluating blunt abdominal trauma for patients presenting to the emergency department. Electronic search of Scopus and Pubmed was performed from inception to September 2016. Human studies investigating...

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Autores principales: Zhongheng Zhang, Yucai Hong, Ning Liu, Yuhao Chen
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Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ea0437a3c117408983d2a137fe7e1977
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spelling oai:doaj.org-article:ea0437a3c117408983d2a137fe7e19772021-12-02T11:51:03ZDiagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis10.1038/s41598-017-04779-22045-2322https://doaj.org/article/ea0437a3c117408983d2a137fe7e19772017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-04779-2https://doaj.org/toc/2045-2322Abstract We aimed to investigate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in evaluating blunt abdominal trauma for patients presenting to the emergency department. Electronic search of Scopus and Pubmed was performed from inception to September 2016. Human studies investigating the diagnostic accuracy of CEUS in identifying abdominal solid organ injuries were included. Risk of bias was assessed using the QUADAS tool. A total of 10 studies were included in the study and 9 of them were included for meta-analysis. The log(DOR) values ranged from 3.80 (95% CI: 2.81–4.79) to 8.52 (95% CI: 4.58–12.47) in component studies. The combined log(DOR) was 6.56 (95% CI: 5.66–7.45). The Cochran’s Q was 11.265 (p = 0.793 with 16 degrees of freedom), and the Higgins’ I2 was 0%. The CEUS had a sensitivity of 0.981 (95% CI: 0.868–0.950) and a false positive rate of 0.018 (95% CI: 0.010–0.032) for identifying parenchymal injuries, with an AUC of 0.984. CEUS performed at emergency department had good diagnostic accuracy in identifying abdominal solid organ injuries. CEUS can be recommended in monitoring solid organ injuries, especially for patients managed with non-operative strategy.Zhongheng ZhangYucai HongNing LiuYuhao ChenNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Zhongheng Zhang
Yucai Hong
Ning Liu
Yuhao Chen
Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
description Abstract We aimed to investigate the diagnostic accuracy of contrast-enhanced ultrasound (CEUS) in evaluating blunt abdominal trauma for patients presenting to the emergency department. Electronic search of Scopus and Pubmed was performed from inception to September 2016. Human studies investigating the diagnostic accuracy of CEUS in identifying abdominal solid organ injuries were included. Risk of bias was assessed using the QUADAS tool. A total of 10 studies were included in the study and 9 of them were included for meta-analysis. The log(DOR) values ranged from 3.80 (95% CI: 2.81–4.79) to 8.52 (95% CI: 4.58–12.47) in component studies. The combined log(DOR) was 6.56 (95% CI: 5.66–7.45). The Cochran’s Q was 11.265 (p = 0.793 with 16 degrees of freedom), and the Higgins’ I2 was 0%. The CEUS had a sensitivity of 0.981 (95% CI: 0.868–0.950) and a false positive rate of 0.018 (95% CI: 0.010–0.032) for identifying parenchymal injuries, with an AUC of 0.984. CEUS performed at emergency department had good diagnostic accuracy in identifying abdominal solid organ injuries. CEUS can be recommended in monitoring solid organ injuries, especially for patients managed with non-operative strategy.
format article
author Zhongheng Zhang
Yucai Hong
Ning Liu
Yuhao Chen
author_facet Zhongheng Zhang
Yucai Hong
Ning Liu
Yuhao Chen
author_sort Zhongheng Zhang
title Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
title_short Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
title_full Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
title_fullStr Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
title_full_unstemmed Diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
title_sort diagnostic accuracy of contrast enhanced ultrasound in patients with blunt abdominal trauma presenting to the emergency department: a systematic review and meta-analysis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/ea0437a3c117408983d2a137fe7e1977
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AT yucaihong diagnosticaccuracyofcontrastenhancedultrasoundinpatientswithbluntabdominaltraumapresentingtotheemergencydepartmentasystematicreviewandmetaanalysis
AT ningliu diagnosticaccuracyofcontrastenhancedultrasoundinpatientswithbluntabdominaltraumapresentingtotheemergencydepartmentasystematicreviewandmetaanalysis
AT yuhaochen diagnosticaccuracyofcontrastenhancedultrasoundinpatientswithbluntabdominaltraumapresentingtotheemergencydepartmentasystematicreviewandmetaanalysis
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