Therapeutic inhibition of GAS6-AS1/YBX1/MYC axis suppresses cell propagation and disease progression of acute myeloid leukemia

Abstract Background Acute myeloid leukemia (AML) is the most common type of leukemia in adults. Its therapy has not significantly improved during the past four decades despite intense research efforts. New molecularly targeted therapies are in great need. The proto-oncogene c-Myc (MYC) is an attract...

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Autores principales: Hao Zhou, Wei Liu, Yongming Zhou, Zhenya Hong, Jian Ni, Xiaoping Zhang, Ziping Li, Mengyuan Li, Wenjuan He, Donghua Zhang, Xuexing Chen, Jianhua Zhu
Formato: article
Lenguaje:EN
Publicado: BMC 2021
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MYC
Acceso en línea:https://doaj.org/article/ea05389eaa4442eea576c26ad9e9992d
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