Improved identification of concordant and discordant gene expression signatures using an updated rank-rank hypergeometric overlap approach

Abstract Recent advances in large-scale gene expression profiling necessitate concurrent development of biostatistical approaches to reveal meaningful biological relationships. Most analyses rely on significance thresholds for identifying differentially expressed genes. We use an approach to compare...

Full description

Saved in:
Bibliographic Details
Main Authors: Kelly M. Cahill, Zhiguang Huo, George C. Tseng, Ryan W. Logan, Marianne L. Seney
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
R
Q
Online Access:https://doaj.org/article/ea08d28b830a44899508fdecbeb39c8d
Tags: Add Tag
No Tags, Be the first to tag this record!