Simulations suggest a constrictive force is required for Gram-negative bacterial cell division

It is unclear whether a constrictive force is exerted on the membrane from inside during bacterial cell division, or cell wall remodeling alone drives membrane constriction from outside. Here, the authors use simulations to explore different mechanisms for cell wall division, supporting that a const...

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Bibliographic Details
Main Authors: Lam T. Nguyen, Catherine M. Oikonomou, H. Jane Ding, Mohammed Kaplan, Qing Yao, Yi-Wei Chang, Morgan Beeby, Grant J. Jensen
Format: article
Language:EN
Published: Nature Portfolio 2019
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Online Access:https://doaj.org/article/ea0967d0660942c98c1305a82e9eadc5
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Summary:It is unclear whether a constrictive force is exerted on the membrane from inside during bacterial cell division, or cell wall remodeling alone drives membrane constriction from outside. Here, the authors use simulations to explore different mechanisms for cell wall division, supporting that a constrictive force is required.