Ploidy dynamics increase the risk of liver cancer initiation

Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.

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Detalles Bibliográficos
Autores principales:	Miryam Müller, Stephanie May, Thomas G. Bird
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ea16fd4d88ff412c8ba1f06de4b0cf60
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spelling	oai:doaj.org-article:ea16fd4d88ff412c8ba1f06de4b0cf602021-12-02T17:04:31ZPloidy dynamics increase the risk of liver cancer initiation10.1038/s41467-021-21897-82041-1723https://doaj.org/article/ea16fd4d88ff412c8ba1f06de4b0cf602021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21897-8https://doaj.org/toc/2041-1723Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.Miryam MüllerStephanie MayThomas G. BirdNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-4 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Miryam Müller Stephanie May Thomas G. Bird Ploidy dynamics increase the risk of liver cancer initiation
description	Liver cancer typically arises after years of inflammatory insults to hepatocytes. These cells can change their ploidy state during health and disease. Whilst polyploidy may offer some protection, new research shows it may also promote the formation of liver tumours.
format	article
author	Miryam Müller Stephanie May Thomas G. Bird
author_facet	Miryam Müller Stephanie May Thomas G. Bird
author_sort	Miryam Müller
title	Ploidy dynamics increase the risk of liver cancer initiation
title_short	Ploidy dynamics increase the risk of liver cancer initiation
title_full	Ploidy dynamics increase the risk of liver cancer initiation
title_fullStr	Ploidy dynamics increase the risk of liver cancer initiation
title_full_unstemmed	Ploidy dynamics increase the risk of liver cancer initiation
title_sort	ploidy dynamics increase the risk of liver cancer initiation
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ea16fd4d88ff412c8ba1f06de4b0cf60
work_keys_str_mv	AT miryammuller ploidydynamicsincreasetheriskoflivercancerinitiation AT stephaniemay ploidydynamicsincreasetheriskoflivercancerinitiation AT thomasgbird ploidydynamicsincreasetheriskoflivercancerinitiation
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Ploidy dynamics increase the risk of liver cancer initiation

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