Global Mapping of the Macrophage-HIV-1 Transcriptome Reveals that Productive Infection Induces Remodeling of Host Cell DNA and Chromatin

Abstract It has been proposed that macrophages could serve as long-lived compartments for HIV-1 infection under in vivo situations because these cells are resistant to the virus-mediated cytopathic effect, produce progeny virus over extended periods of time and are localized in tissues that are ofte...

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Autores principales: Alexandre Deshiere, Charles Joly-Beauparlant, Yann Breton, Michel Ouellet, Frédéric Raymond, Robert Lodge, Corinne Barat, Marc-André Roy, Jacques Corbeil, Michel J. Tremblay
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/ea2329ad91314c6c8c74950e07bd5937
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