Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths
Sagar B Patel,1,2 Nisha Reddy,2 Xihui Lin,1,2 Jess T Whitson1,2 1Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA; 2Department of Ophthalmology, University of Texas Southwestern Medical School, Dallas, TX, USA Purpose: To evaluate the relationship betwe...
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Dove Medical Press
2018
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oai:doaj.org-article:ea28577a234f4013874c5f913036f8242021-12-02T05:16:55ZOptical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths1177-5483https://doaj.org/article/ea28577a234f4013874c5f913036f8242018-05-01T00:00:00Zhttps://www.dovepress.com/optical-coherence-tomography-retinal-nerve-fiber-layer-analysis-in-eye-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Sagar B Patel,1,2 Nisha Reddy,2 Xihui Lin,1,2 Jess T Whitson1,2 1Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA; 2Department of Ophthalmology, University of Texas Southwestern Medical School, Dallas, TX, USA Purpose: To evaluate the relationship between axial length (AL) and retinal nerve fiber layer (RNFL) profile and to characterize differences in optical coherence tomography RNFL of myopic glaucomatous eyes compared to nonglaucomatous eyes. Methods: Retrospective chart review of 170 eyes of 89 subjects with optical biometry and optical coherence tomography RNFL assessment was conducted. Results: Temporal RNFL thickness showed no association with AL in either glaucomatous or nonglaucomatous eyes. Nasal thinning was most strongly associated with glaucoma in myopic eyes. Both myopic glaucomatous and nonglaucomatous eyes had a mean RNFL thickness of 16–22 µm thinner than mean RNFL thickness of normal AL eyes. Conclusion: An average of 16–22 µm thinning of RNFL compared to nomogram can be tolerated in patients with long AL. Prominent nasal thinning likely represents changes from axial elongation. Temporal RNFL thinning in those with long AL tends to be mild, and significant thinning should raise suspicion for glaucoma. Keywords: myopia, axial length, ocular coherence tomography retinal nerve fiber layer (OCT RNFL), glaucomaPatel SBReddy NLin XWhitson JTDove Medical PressarticleMyopiaaxial-lengthocular coherence tomography retinal nerve fiber layer (OCT RNFL)glaucoma.OphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 12, Pp 827-832 (2018) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Myopia axial-length ocular coherence tomography retinal nerve fiber layer (OCT RNFL) glaucoma. Ophthalmology RE1-994 |
| spellingShingle |
Myopia axial-length ocular coherence tomography retinal nerve fiber layer (OCT RNFL) glaucoma. Ophthalmology RE1-994 Patel SB Reddy N Lin X Whitson JT Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| description |
Sagar B Patel,1,2 Nisha Reddy,2 Xihui Lin,1,2 Jess T Whitson1,2 1Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, TX, USA; 2Department of Ophthalmology, University of Texas Southwestern Medical School, Dallas, TX, USA Purpose: To evaluate the relationship between axial length (AL) and retinal nerve fiber layer (RNFL) profile and to characterize differences in optical coherence tomography RNFL of myopic glaucomatous eyes compared to nonglaucomatous eyes. Methods: Retrospective chart review of 170 eyes of 89 subjects with optical biometry and optical coherence tomography RNFL assessment was conducted. Results: Temporal RNFL thickness showed no association with AL in either glaucomatous or nonglaucomatous eyes. Nasal thinning was most strongly associated with glaucoma in myopic eyes. Both myopic glaucomatous and nonglaucomatous eyes had a mean RNFL thickness of 16–22 µm thinner than mean RNFL thickness of normal AL eyes. Conclusion: An average of 16–22 µm thinning of RNFL compared to nomogram can be tolerated in patients with long AL. Prominent nasal thinning likely represents changes from axial elongation. Temporal RNFL thinning in those with long AL tends to be mild, and significant thinning should raise suspicion for glaucoma. Keywords: myopia, axial length, ocular coherence tomography retinal nerve fiber layer (OCT RNFL), glaucoma |
| format |
article |
| author |
Patel SB Reddy N Lin X Whitson JT |
| author_facet |
Patel SB Reddy N Lin X Whitson JT |
| author_sort |
Patel SB |
| title |
Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| title_short |
Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| title_full |
Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| title_fullStr |
Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| title_full_unstemmed |
Optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| title_sort |
optical coherence tomography retinal nerve fiber layer analysis in eyes with long axial lengths |
| publisher |
Dove Medical Press |
| publishDate |
2018 |
| url |
https://doaj.org/article/ea28577a234f4013874c5f913036f824 |
| work_keys_str_mv |
AT patelsb opticalcoherencetomographyretinalnervefiberlayeranalysisineyeswithlongaxiallengths AT reddyn opticalcoherencetomographyretinalnervefiberlayeranalysisineyeswithlongaxiallengths AT linx opticalcoherencetomographyretinalnervefiberlayeranalysisineyeswithlongaxiallengths AT whitsonjt opticalcoherencetomographyretinalnervefiberlayeranalysisineyeswithlongaxiallengths |
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