Mitochondrial augmentation of CD34+ cells from healthy donors and patients with mitochondrial DNA disorders confers functional benefit
Abstract Mitochondria are cellular organelles critical for numerous cellular processes and harboring their own circular mitochondrial DNA (mtDNA). Most mtDNA associated disorders (either deletions, mutations, or depletion) lead to multisystemic disease, often severe at a young age, with no disease-m...
Guardado en:
Autores principales: | Elad Jacoby, Moriya Ben Yakir-Blumkin, Shiri Blumenfeld-Kan, Yehuda Brody, Amilia Meir, Naomi Melamed-Book, Tina Napso, Gat Pozner, Esraa Saadi, Ayelet Shabtay-Orbach, Natalie Yivgi-Ohana, Noa Sher, Amos Toren |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ea28dd8efa07497c88f0f158a175ba5b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Mitochondrial dysfunction in neurological disorders: Exploring mitochondrial transplantation
por: Pedro Norat, et al.
Publicado: (2020) - Mitochondrial DNA.
- Mitochondrial DNA.
-
The mitochondrial type IB topoisomerase drives mitochondrial translation and carcinogenesis
por: S. A. Baechler, et al.
Publicado: (2019) -
Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division
por: Bongki Cho, et al.
Publicado: (2017)