Characterization of a group of MITEs with unusual features from two coral genomes.

<h4>Background</h4>Miniature inverted-repeat transposable elements (MITEs), which are common in eukaryotic genomes, are small non-coding elements that transpose by utilizing transposases encoded by autonomous transposons. Recent genome-wide analyses and cross-mobilization assays have gre...

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Autores principales:	Shi Wang, Lingling Zhang, Eli Meyer, Mikhail V Matz
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2010
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ea3c6a03024d4299ba855b0063db8add
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spelling	oai:doaj.org-article:ea3c6a03024d4299ba855b0063db8add2021-12-02T20:21:36ZCharacterization of a group of MITEs with unusual features from two coral genomes.1932-620310.1371/journal.pone.0010700https://doaj.org/article/ea3c6a03024d4299ba855b0063db8add2010-05-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20502527/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Miniature inverted-repeat transposable elements (MITEs), which are common in eukaryotic genomes, are small non-coding elements that transpose by utilizing transposases encoded by autonomous transposons. Recent genome-wide analyses and cross-mobilization assays have greatly improved our knowledge on MITE proliferation, however, specific mechanisms for the origin and evolution of MITEs are still unclear.<h4>Principal findings</h4>A group of coral MITEs called CMITE were identified from two corals, Acropora millepora and Acropora palmata. CMITEs conform to many common characteristics of MITEs, but also present several unusual features. The most unusual feature of CMITEs is conservation of the internal region, which is more conserved between MITE families than the TIRs. The origin of this internal region remains unknown, although we found one CMITE family that seems to be derived from a piggyBac-like transposon in A. millepora. CMITEs can form tandem arrays, suggesting an unconventional way for MITEs to increase copy numbers. We also describe a case in which a novel transposable element was created by a CMITE insertion event.<h4>Conclusions</h4>To our knowledge, this is the first report of identification of MITEs from coral genomes. Proliferation of CMITEs seems to be related to the transposition machinery of piggyBac-like autonomous transposons. The highly conserved internal region of CMITEs suggests a potential role for this region in their successful transposition. However, the origin of these unusual features in CMITEs remains unclear, and thus represents an intriguing topic for future investigations.Shi WangLingling ZhangEli MeyerMikhail V MatzPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 5, Iss 5, p e10700 (2010)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shi Wang Lingling Zhang Eli Meyer Mikhail V Matz Characterization of a group of MITEs with unusual features from two coral genomes.
description	<h4>Background</h4>Miniature inverted-repeat transposable elements (MITEs), which are common in eukaryotic genomes, are small non-coding elements that transpose by utilizing transposases encoded by autonomous transposons. Recent genome-wide analyses and cross-mobilization assays have greatly improved our knowledge on MITE proliferation, however, specific mechanisms for the origin and evolution of MITEs are still unclear.<h4>Principal findings</h4>A group of coral MITEs called CMITE were identified from two corals, Acropora millepora and Acropora palmata. CMITEs conform to many common characteristics of MITEs, but also present several unusual features. The most unusual feature of CMITEs is conservation of the internal region, which is more conserved between MITE families than the TIRs. The origin of this internal region remains unknown, although we found one CMITE family that seems to be derived from a piggyBac-like transposon in A. millepora. CMITEs can form tandem arrays, suggesting an unconventional way for MITEs to increase copy numbers. We also describe a case in which a novel transposable element was created by a CMITE insertion event.<h4>Conclusions</h4>To our knowledge, this is the first report of identification of MITEs from coral genomes. Proliferation of CMITEs seems to be related to the transposition machinery of piggyBac-like autonomous transposons. The highly conserved internal region of CMITEs suggests a potential role for this region in their successful transposition. However, the origin of these unusual features in CMITEs remains unclear, and thus represents an intriguing topic for future investigations.
format	article
author	Shi Wang Lingling Zhang Eli Meyer Mikhail V Matz
author_facet	Shi Wang Lingling Zhang Eli Meyer Mikhail V Matz
author_sort	Shi Wang
title	Characterization of a group of MITEs with unusual features from two coral genomes.
title_short	Characterization of a group of MITEs with unusual features from two coral genomes.
title_full	Characterization of a group of MITEs with unusual features from two coral genomes.
title_fullStr	Characterization of a group of MITEs with unusual features from two coral genomes.
title_full_unstemmed	Characterization of a group of MITEs with unusual features from two coral genomes.
title_sort	characterization of a group of mites with unusual features from two coral genomes.
publisher	Public Library of Science (PLoS)
publishDate	2010
url	https://doaj.org/article/ea3c6a03024d4299ba855b0063db8add
work_keys_str_mv	AT shiwang characterizationofagroupofmiteswithunusualfeaturesfromtwocoralgenomes AT linglingzhang characterizationofagroupofmiteswithunusualfeaturesfromtwocoralgenomes AT elimeyer characterizationofagroupofmiteswithunusualfeaturesfromtwocoralgenomes AT mikhailvmatz characterizationofagroupofmiteswithunusualfeaturesfromtwocoralgenomes
_version_	1718374140064301056

Characterization of a group of MITEs with unusual features from two coral genomes.

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