Metagenome-Wide Analysis of Rural and Urban Surface Waters and Sediments in Bangladesh Identifies Human Waste as a Driver of Antibiotic Resistance

Low- and middle-income countries (LMICs) have higher burdens of multidrug-resistant infections than high-income countries, and there is thus an urgent need to elucidate the drivers of the spread of antibiotic-resistant bacteria in LMICs. Here, we study the diversity and abundance of antibiotic resi...

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Auteurs principaux: Ross Stuart McInnes, Md Hassan uz-Zaman, Imam Taskin Alam, Siu Fung Stanley Ho, Robert A. Moran, John D. Clemens, Md Sirajul Islam, Willem van Schaik
Format: article
Langue:EN
Publié: American Society for Microbiology 2021
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Accès en ligne:https://doaj.org/article/ea444a4b51fd4c72bd2c5df2b07d557a
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Résumé:Low- and middle-income countries (LMICs) have higher burdens of multidrug-resistant infections than high-income countries, and there is thus an urgent need to elucidate the drivers of the spread of antibiotic-resistant bacteria in LMICs. Here, we study the diversity and abundance of antibiotic resistance genes in surface water and sediments from rural and urban settings in Bangladesh.