Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.

<h4>Setting</h4>A South African township clinic where loss to follow-up during TB treatment may prevent HIV-infected TB patients from receiving life-saving ART.<h4>Objective</h4>To determine factors associated with loss to follow-up during TB treatment.<h4>Design</h4...

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Autores principales:	Dominique J Pepper, Suzaan Marais, Feriyl Bhaijee, Robert J Wilkinson, Virginia De Azevedo, Graeme Meintjes
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ea4b51aead9548ee9d72613a10d26df5
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spelling	oai:doaj.org-article:ea4b51aead9548ee9d72613a10d26df52021-11-18T07:15:18ZAssessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.1932-620310.1371/journal.pone.0037634https://doaj.org/article/ea4b51aead9548ee9d72613a10d26df52012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22719843/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Setting</h4>A South African township clinic where loss to follow-up during TB treatment may prevent HIV-infected TB patients from receiving life-saving ART.<h4>Objective</h4>To determine factors associated with loss to follow-up during TB treatment.<h4>Design</h4>Regression analyses of a cohort of ART-eligible TB patients who commenced TB treatment and were followed for 24 weeks.<h4>Results</h4>Of 111 ART-eligible TB patients, 15 (14%) died in the ensuing 24 weeks. Of the remaining 96 TB patients, 11 (11%) were lost to follow-up. All TB patients lost to follow-up did not initiate ART. Of 85 TB patients in follow-up, 62 (73%) initiated ART 56 days after TB diagnosis (median, IQR 33-77 days) and 31 days after initial assessment at an ART clinic (median, IQR: 18-55 days). The median duration from TB diagnosis to initial assessment at an ART clinic was 19 days (IQR: 7-48 days). At 24 weeks, 6 of 85 (7%) TB patients who presented to an ART clinic for assessment were lost to follow-up, compared to 5 of 11 (45%) TB patients who did not present to an ART clinic for assessment. Logistic regression analysis (adjusted odds ratio = 0.1, 95% confidence interval [95% CI]: 0.03-0.66) and our Cox proportional hazards model (hazard ratio = 0.2, 95% CI: 0.04-0.68) confirmed that assessment at an ART clinic during TB treatment reduced loss to follow-up.<h4>Conclusion</h4>Assessment at antiretroviral clinics for HIV care by trained health-care providers reduces loss to follow-up among HIV-infected patients with TB.Dominique J PepperSuzaan MaraisFeriyl BhaijeeRobert J WilkinsonVirginia De AzevedoGraeme MeintjesPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 6, p e37634 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dominique J Pepper Suzaan Marais Feriyl Bhaijee Robert J Wilkinson Virginia De Azevedo Graeme Meintjes Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
description	<h4>Setting</h4>A South African township clinic where loss to follow-up during TB treatment may prevent HIV-infected TB patients from receiving life-saving ART.<h4>Objective</h4>To determine factors associated with loss to follow-up during TB treatment.<h4>Design</h4>Regression analyses of a cohort of ART-eligible TB patients who commenced TB treatment and were followed for 24 weeks.<h4>Results</h4>Of 111 ART-eligible TB patients, 15 (14%) died in the ensuing 24 weeks. Of the remaining 96 TB patients, 11 (11%) were lost to follow-up. All TB patients lost to follow-up did not initiate ART. Of 85 TB patients in follow-up, 62 (73%) initiated ART 56 days after TB diagnosis (median, IQR 33-77 days) and 31 days after initial assessment at an ART clinic (median, IQR: 18-55 days). The median duration from TB diagnosis to initial assessment at an ART clinic was 19 days (IQR: 7-48 days). At 24 weeks, 6 of 85 (7%) TB patients who presented to an ART clinic for assessment were lost to follow-up, compared to 5 of 11 (45%) TB patients who did not present to an ART clinic for assessment. Logistic regression analysis (adjusted odds ratio = 0.1, 95% confidence interval [95% CI]: 0.03-0.66) and our Cox proportional hazards model (hazard ratio = 0.2, 95% CI: 0.04-0.68) confirmed that assessment at an ART clinic during TB treatment reduced loss to follow-up.<h4>Conclusion</h4>Assessment at antiretroviral clinics for HIV care by trained health-care providers reduces loss to follow-up among HIV-infected patients with TB.
format	article
author	Dominique J Pepper Suzaan Marais Feriyl Bhaijee Robert J Wilkinson Virginia De Azevedo Graeme Meintjes
author_facet	Dominique J Pepper Suzaan Marais Feriyl Bhaijee Robert J Wilkinson Virginia De Azevedo Graeme Meintjes
author_sort	Dominique J Pepper
title	Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
title_short	Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
title_full	Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
title_fullStr	Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
title_full_unstemmed	Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.
title_sort	assessment at antiretroviral clinics during tb treatment reduces loss to follow-up among hiv-infected patients.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/ea4b51aead9548ee9d72613a10d26df5
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Assessment at antiretroviral clinics during TB treatment reduces loss to follow-up among HIV-infected patients.

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