Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors

Summary: Projections from sensory neurons of olfactory systems coalesce into glomeruli in the brain. The Kirrel receptors are believed to homodimerize via their ectodomains and help separate sensory neuron axons into Kirrel2- or Kirrel3-expressing glomeruli. Here, we present the crystal structures o...

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Autores principales: Jing Wang, Neelima Vaddadi, Joseph S. Pak, Yeonwoo Park, Sabrina Quilez, Christina A. Roman, Emilie Dumontier, Joseph W. Thornton, Jean-François Cloutier, Engin Özkan
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/ea566befb1714a608858eb1ec6016712
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