Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes

Meiotic recombination density is increased on shorter chromosomes. Here the authors show that recombination initiation continues near all chromosome ends long after interstitial regions become quiescent in a process that proportionally benefits short chromosomes.

Guardado en:

Detalles Bibliográficos
Autores principales:	Vijayalakshmi V. Subramanian, Xuan Zhu, Tovah E. Markowitz, Luis A. Vale-Silva, Pedro A. San-Segundo, Nancy M. Hollingsworth, Scott Keeney, Andreas Hochwagen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ea5a09e10b4b468fb01ea1d0f4fada81
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:ea5a09e10b4b468fb01ea1d0f4fada81
record_format	dspace
spelling	oai:doaj.org-article:ea5a09e10b4b468fb01ea1d0f4fada812021-12-02T15:35:36ZPersistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes10.1038/s41467-019-08875-x2041-1723https://doaj.org/article/ea5a09e10b4b468fb01ea1d0f4fada812019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08875-xhttps://doaj.org/toc/2041-1723Meiotic recombination density is increased on shorter chromosomes. Here the authors show that recombination initiation continues near all chromosome ends long after interstitial regions become quiescent in a process that proportionally benefits short chromosomes.Vijayalakshmi V. SubramanianXuan ZhuTovah E. MarkowitzLuis A. Vale-SilvaPedro A. San-SegundoNancy M. HollingsworthScott KeeneyAndreas HochwagenNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Vijayalakshmi V. Subramanian Xuan Zhu Tovah E. Markowitz Luis A. Vale-Silva Pedro A. San-Segundo Nancy M. Hollingsworth Scott Keeney Andreas Hochwagen Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
description	Meiotic recombination density is increased on shorter chromosomes. Here the authors show that recombination initiation continues near all chromosome ends long after interstitial regions become quiescent in a process that proportionally benefits short chromosomes.
format	article
author	Vijayalakshmi V. Subramanian Xuan Zhu Tovah E. Markowitz Luis A. Vale-Silva Pedro A. San-Segundo Nancy M. Hollingsworth Scott Keeney Andreas Hochwagen
author_facet	Vijayalakshmi V. Subramanian Xuan Zhu Tovah E. Markowitz Luis A. Vale-Silva Pedro A. San-Segundo Nancy M. Hollingsworth Scott Keeney Andreas Hochwagen
author_sort	Vijayalakshmi V. Subramanian
title	Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
title_short	Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
title_full	Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
title_fullStr	Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
title_full_unstemmed	Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
title_sort	persistent dna-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ea5a09e10b4b468fb01ea1d0f4fada81
work_keys_str_mv	AT vijayalakshmivsubramanian persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT xuanzhu persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT tovahemarkowitz persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT luisavalesilva persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT pedroasansegundo persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT nancymhollingsworth persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT scottkeeney persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes AT andreashochwagen persistentdnabreakpotentialneartelomeresincreasesinitiationofmeioticrecombinationonshortchromosomes
_version_	1718386508036046848

Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes

Ejemplares similares