Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling

The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely understood. Here, the authors show that the effects of...

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Autores principales:	Ryan Hamnett, Priya Crosby, Johanna E. Chesham, Michael H. Hastings
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ea608d087ba94ebf8d57d0b5f053090e
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spelling	oai:doaj.org-article:ea608d087ba94ebf8d57d0b5f053090e2021-12-02T16:58:05ZVasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling10.1038/s41467-019-08427-32041-1723https://doaj.org/article/ea608d087ba94ebf8d57d0b5f053090e2019-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08427-3https://doaj.org/toc/2041-1723The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely understood. Here, the authors show that the effects of VIP on the SCN are mediated by ERK1/2 and DUSP4.Ryan HamnettPriya CrosbyJohanna E. CheshamMichael H. HastingsNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ryan Hamnett Priya Crosby Johanna E. Chesham Michael H. Hastings Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
description	The suprachiasmatic nucleus (SCN) synchronises daily rhythms of behaviour and physiology to the light-dark cycle. Vasoactive intestinal peptide (VIP) is important for mediating SCN entrainment; however, the underlying mechanisms are incompletely understood. Here, the authors show that the effects of VIP on the SCN are mediated by ERK1/2 and DUSP4.
format	article
author	Ryan Hamnett Priya Crosby Johanna E. Chesham Michael H. Hastings
author_facet	Ryan Hamnett Priya Crosby Johanna E. Chesham Michael H. Hastings
author_sort	Ryan Hamnett
title	Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
title_short	Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
title_full	Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
title_fullStr	Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
title_full_unstemmed	Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling
title_sort	vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via erk1/2 and dusp4 signalling
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/ea608d087ba94ebf8d57d0b5f053090e
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_version_	1718382421286584320

Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling

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