CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX

Objective: Chylothorax is the leakage of chylous contents into the pleural space as a result of damage to the thoracic duct. Chylous effusion is seen often unilateral but may be bilateral rarely. Etiology includes non-traumatic and traumatic causes. While sarcoidosis, amyloidosis, superior vena cava...

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Autores principales:	Senem MARAL, Murat ALBAYRAK, Berna AFACAN ÖZTÜRK, Merih REİS ARAS, Fatma YILMAZ, Pınar Tığlıoğlu, Mesut TIĞLIOĞLU, Buğra SAĞLAM
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Diseases of the blood and blood-forming organs RC633-647.5
Acceso en línea:	https://doaj.org/article/ea6bd6b6ebb840f9859edd542361983c
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spelling	oai:doaj.org-article:ea6bd6b6ebb840f9859edd542361983c2021-11-10T04:36:08ZCASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX2531-137910.1016/j.htct.2021.10.1039https://doaj.org/article/ea6bd6b6ebb840f9859edd542361983c2021-11-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S253113792101186Xhttps://doaj.org/toc/2531-1379Objective: Chylothorax is the leakage of chylous contents into the pleural space as a result of damage to the thoracic duct. Chylous effusion is seen often unilateral but may be bilateral rarely. Etiology includes non-traumatic and traumatic causes. While sarcoidosis, amyloidosis, superior vena cava thrombosis and congenital anomalies are non-traumatic causes, non-Hodgkin lymphomas are the most common causes.Herein, we present a follicular lymphoma patient who was presented chylothorax at diagnosis. Case report: A 31-year-old male patient presented with fatigue, and dyspnea. On physical examination, inguinal and axillary multiple palpable lymphadenopathies (LAP) were observed, and respiratory sounds were significantly decreased on the left side.Computed tomography imaging revealed prevascular, paratracheal, subcarinal LAPs and 5 cm thick pleural effusion in the deepest part and compression atelectasison the left. Excisional LAP biopsy revealed follicular lymphoma Methodology: When thoracentesis was performed and milky effusion was classified as an exudative. The high triglyceride level was consistent with a chylous effusion. After 6 cycles of R-CHOP treatment, the patient had a significant regression in the initial LAPs, while the chylous effusion persisted. When cytological examination of thoracentesis did not reveal lymphoma, the patient was followed-up. Conclusion: Chylothorax is associated with significant morbidity and mortality if left untreated. Control of the underlying malignancy is still the mainstay of treatment and reported as the most effective. In the literature, successful results were reported with the treatment of the underlying lymphoma. owever, it is known, chylothorax may recur and patients should be follow-up closely.Senem MARALMurat ALBAYRAKBerna AFACAN ÖZTÜRKMerih REİS ARASFatma YILMAZPınar TığlıoğluMesut TIĞLIOĞLUBuğra SAĞLAMElsevierarticleDiseases of the blood and blood-forming organsRC633-647.5ENHematology, Transfusion and Cell Therapy, Vol 43, Iss , Pp S43- (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the blood and blood-forming organs RC633-647.5
spellingShingle	Diseases of the blood and blood-forming organs RC633-647.5 Senem MARAL Murat ALBAYRAK Berna AFACAN ÖZTÜRK Merih REİS ARAS Fatma YILMAZ Pınar Tığlıoğlu Mesut TIĞLIOĞLU Buğra SAĞLAM CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
description	Objective: Chylothorax is the leakage of chylous contents into the pleural space as a result of damage to the thoracic duct. Chylous effusion is seen often unilateral but may be bilateral rarely. Etiology includes non-traumatic and traumatic causes. While sarcoidosis, amyloidosis, superior vena cava thrombosis and congenital anomalies are non-traumatic causes, non-Hodgkin lymphomas are the most common causes.Herein, we present a follicular lymphoma patient who was presented chylothorax at diagnosis. Case report: A 31-year-old male patient presented with fatigue, and dyspnea. On physical examination, inguinal and axillary multiple palpable lymphadenopathies (LAP) were observed, and respiratory sounds were significantly decreased on the left side.Computed tomography imaging revealed prevascular, paratracheal, subcarinal LAPs and 5 cm thick pleural effusion in the deepest part and compression atelectasison the left. Excisional LAP biopsy revealed follicular lymphoma Methodology: When thoracentesis was performed and milky effusion was classified as an exudative. The high triglyceride level was consistent with a chylous effusion. After 6 cycles of R-CHOP treatment, the patient had a significant regression in the initial LAPs, while the chylous effusion persisted. When cytological examination of thoracentesis did not reveal lymphoma, the patient was followed-up. Conclusion: Chylothorax is associated with significant morbidity and mortality if left untreated. Control of the underlying malignancy is still the mainstay of treatment and reported as the most effective. In the literature, successful results were reported with the treatment of the underlying lymphoma. owever, it is known, chylothorax may recur and patients should be follow-up closely.
format	article
author	Senem MARAL Murat ALBAYRAK Berna AFACAN ÖZTÜRK Merih REİS ARAS Fatma YILMAZ Pınar Tığlıoğlu Mesut TIĞLIOĞLU Buğra SAĞLAM
author_facet	Senem MARAL Murat ALBAYRAK Berna AFACAN ÖZTÜRK Merih REİS ARAS Fatma YILMAZ Pınar Tığlıoğlu Mesut TIĞLIOĞLU Buğra SAĞLAM
author_sort	Senem MARAL
title	CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
title_short	CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
title_full	CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
title_fullStr	CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
title_full_unstemmed	CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX
title_sort	case report: follicular lymphoma presented with chylothorax
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/ea6bd6b6ebb840f9859edd542361983c
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CASE REPORT: FOLLICULAR LYMPHOMA PRESENTED WITH CHYLOTHORAX

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