Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes

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Autores principales:	Kazuhiro Kakimi, Hirokazu Matsushita, Masaaki Komatsu, Eiryo Kawakami, Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, Keita Koseki, Eiji Warabi, Tomoyuki Ohue, Katsuyuki Shiroguchi, Heiichiro Udono
Formato:	article
Lenguaje:	EN
Publicado:	BMJ Publishing Group 2021
Materias:	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/ea6e95b1875f4efea28894d8d086bffc
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spelling	oai:doaj.org-article:ea6e95b1875f4efea28894d8d086bffc2021-11-12T12:30:05ZMitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes10.1136/jitc-2021-0029542051-1426https://doaj.org/article/ea6e95b1875f4efea28894d8d086bffc2021-09-01T00:00:00Zhttps://jitc.bmj.com/content/9/9/e002954.fullhttps://doaj.org/toc/2051-1426Kazuhiro KakimiHirokazu MatsushitaMasaaki KomatsuEiryo KawakamiMikako NishidaNahoko YamashitaTaisaku OgawaKeita KosekiEiji WarabiTomoyuki OhueKatsuyuki ShiroguchiHeiichiro UdonoBMJ Publishing GrouparticleNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENJournal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Kazuhiro Kakimi Hirokazu Matsushita Masaaki Komatsu Eiryo Kawakami Mikako Nishida Nahoko Yamashita Taisaku Ogawa Keita Koseki Eiji Warabi Tomoyuki Ohue Katsuyuki Shiroguchi Heiichiro Udono Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
format	article
author	Kazuhiro Kakimi Hirokazu Matsushita Masaaki Komatsu Eiryo Kawakami Mikako Nishida Nahoko Yamashita Taisaku Ogawa Keita Koseki Eiji Warabi Tomoyuki Ohue Katsuyuki Shiroguchi Heiichiro Udono
author_facet	Kazuhiro Kakimi Hirokazu Matsushita Masaaki Komatsu Eiryo Kawakami Mikako Nishida Nahoko Yamashita Taisaku Ogawa Keita Koseki Eiji Warabi Tomoyuki Ohue Katsuyuki Shiroguchi Heiichiro Udono
author_sort	Kazuhiro Kakimi
title	Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
title_short	Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
title_full	Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
title_fullStr	Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
title_full_unstemmed	Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes
title_sort	mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of nrf2/mtorc1/p62 axis in tumor-infiltrating cd8t lymphocytes
publisher	BMJ Publishing Group
publishDate	2021
url	https://doaj.org/article/ea6e95b1875f4efea28894d8d086bffc
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Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes

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