Localization of adaptive variants in human genomes using averaged one-dependence estimation

Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.

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Bibliographic Details
Main Authors: Lauren Alpert Sugden, Elizabeth G. Atkinson, Annie P. Fischer, Stephen Rong, Brenna M. Henn, Sohini Ramachandran
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7
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Summary:Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.