Localization of adaptive variants in human genomes using averaged one-dependence estimation
Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.
Guardado en:
Autores principales: | , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:ea7421382bdb46b1aa16c069bc69f1a7 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:ea7421382bdb46b1aa16c069bc69f1a72021-12-02T15:33:34ZLocalization of adaptive variants in human genomes using averaged one-dependence estimation10.1038/s41467-018-03100-72041-1723https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a72018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03100-7https://doaj.org/toc/2041-1723Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.Lauren Alpert SugdenElizabeth G. AtkinsonAnnie P. FischerStephen RongBrenna M. HennSohini RamachandranNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran Localization of adaptive variants in human genomes using averaged one-dependence estimation |
description |
Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San. |
format |
article |
author |
Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran |
author_facet |
Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran |
author_sort |
Lauren Alpert Sugden |
title |
Localization of adaptive variants in human genomes using averaged one-dependence estimation |
title_short |
Localization of adaptive variants in human genomes using averaged one-dependence estimation |
title_full |
Localization of adaptive variants in human genomes using averaged one-dependence estimation |
title_fullStr |
Localization of adaptive variants in human genomes using averaged one-dependence estimation |
title_full_unstemmed |
Localization of adaptive variants in human genomes using averaged one-dependence estimation |
title_sort |
localization of adaptive variants in human genomes using averaged one-dependence estimation |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7 |
work_keys_str_mv |
AT laurenalpertsugden localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT elizabethgatkinson localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT anniepfischer localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT stephenrong localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT brennamhenn localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT sohiniramachandran localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation |
_version_ |
1718387117452689408 |