Localization of adaptive variants in human genomes using averaged one-dependence estimation

Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.

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Auteurs principaux:	Lauren Alpert Sugden, Elizabeth G. Atkinson, Annie P. Fischer, Stephen Rong, Brenna M. Henn, Sohini Ramachandran
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Science Q
Accès en ligne:	https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7
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spelling	oai:doaj.org-article:ea7421382bdb46b1aa16c069bc69f1a72021-12-02T15:33:34ZLocalization of adaptive variants in human genomes using averaged one-dependence estimation10.1038/s41467-018-03100-72041-1723https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a72018-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03100-7https://doaj.org/toc/2041-1723Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.Lauren Alpert SugdenElizabeth G. AtkinsonAnnie P. FischerStephen RongBrenna M. HennSohini RamachandranNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran Localization of adaptive variants in human genomes using averaged one-dependence estimation
description	Selective sweeps are events in which beneficial mutations spread rapidly through a population. Here, Sugden et al. develop SWIF(r), a probabilistic classification framework for detecting and localizing selective sweeps, and apply it to genomic data from the ‡Khomani San.
format	article
author	Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran
author_facet	Lauren Alpert Sugden Elizabeth G. Atkinson Annie P. Fischer Stephen Rong Brenna M. Henn Sohini Ramachandran
author_sort	Lauren Alpert Sugden
title	Localization of adaptive variants in human genomes using averaged one-dependence estimation
title_short	Localization of adaptive variants in human genomes using averaged one-dependence estimation
title_full	Localization of adaptive variants in human genomes using averaged one-dependence estimation
title_fullStr	Localization of adaptive variants in human genomes using averaged one-dependence estimation
title_full_unstemmed	Localization of adaptive variants in human genomes using averaged one-dependence estimation
title_sort	localization of adaptive variants in human genomes using averaged one-dependence estimation
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/ea7421382bdb46b1aa16c069bc69f1a7
work_keys_str_mv	AT laurenalpertsugden localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT elizabethgatkinson localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT anniepfischer localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT stephenrong localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT brennamhenn localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation AT sohiniramachandran localizationofadaptivevariantsinhumangenomesusingaveragedonedependenceestimation
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Localization of adaptive variants in human genomes using averaged one-dependence estimation

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