Association of erectile dysfunction with tinnitus: a nationwide population-based study

Abstract With many previous studies indicating a higher prevalence of sexual problems in patients with tinnitus, the association between tinnitus and erectile dysfunction (ED) has become an interesting topic that warrants further research. In our study, we hypothesized that tinnitus may be associate...

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Autores principales:	Yen-Fu Cheng, Sudha Xirasagar, Nai-Wen Kuo, Shiu-Dong Chung, Herng-Ching Lin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/ea7e7a706cdf4a6f8eed0a308d601539
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spelling	oai:doaj.org-article:ea7e7a706cdf4a6f8eed0a308d6015392021-12-02T17:04:07ZAssociation of erectile dysfunction with tinnitus: a nationwide population-based study10.1038/s41598-021-86441-62045-2322https://doaj.org/article/ea7e7a706cdf4a6f8eed0a308d6015392021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-86441-6https://doaj.org/toc/2045-2322Abstract With many previous studies indicating a higher prevalence of sexual problems in patients with tinnitus, the association between tinnitus and erectile dysfunction (ED) has become an interesting topic that warrants further research. In our study, we hypothesized that tinnitus may be associated with ED and aimed to further explore the relationship between these two medical conditions using a nationwide population-based database. After retrieving data of 19,329 patients with ED and 19,329 propensity score-matched patients without ED (controls) from Taiwan’s National Health Insurance Dataset, we defined the diagnosis date (the date of the first ED claim) for patients with ED as the index date for cases, and the date of the first utilization of ambulatory care by patients without ED during the index year of their matched case as the index date for controls. We found that 1247 out of 38,658 sampled patients (3.23%) had received a tinnitus diagnosis within the year before the index date, with 792 (4.10%) from cases and 455 (2.35%) from controls. We then utilized multiple logistic regression analysis and observed that cases were more likely to have had a prior tinnitus diagnosis compared to controls (OR 1.772; 95% CI 1.577–1.992; p < 0.001). Lastly, we adjusted the data for co-morbid medical disorders and social economic factors, with the end results showing that cases were more likely than controls to have a prior diagnosis of tinnitus (OR 1.779, 95% CI 1.582–2.001, p < 0.001). Through our investigation, we have ultimately detected a novel association between ED and tinnitus and urge physicians to be alert to the possibility of the development of ED in patients treated for tinnitus.Yen-Fu ChengSudha XirasagarNai-Wen KuoShiu-Dong ChungHerng-Ching LinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yen-Fu Cheng Sudha Xirasagar Nai-Wen Kuo Shiu-Dong Chung Herng-Ching Lin Association of erectile dysfunction with tinnitus: a nationwide population-based study
description	Abstract With many previous studies indicating a higher prevalence of sexual problems in patients with tinnitus, the association between tinnitus and erectile dysfunction (ED) has become an interesting topic that warrants further research. In our study, we hypothesized that tinnitus may be associated with ED and aimed to further explore the relationship between these two medical conditions using a nationwide population-based database. After retrieving data of 19,329 patients with ED and 19,329 propensity score-matched patients without ED (controls) from Taiwan’s National Health Insurance Dataset, we defined the diagnosis date (the date of the first ED claim) for patients with ED as the index date for cases, and the date of the first utilization of ambulatory care by patients without ED during the index year of their matched case as the index date for controls. We found that 1247 out of 38,658 sampled patients (3.23%) had received a tinnitus diagnosis within the year before the index date, with 792 (4.10%) from cases and 455 (2.35%) from controls. We then utilized multiple logistic regression analysis and observed that cases were more likely to have had a prior tinnitus diagnosis compared to controls (OR 1.772; 95% CI 1.577–1.992; p < 0.001). Lastly, we adjusted the data for co-morbid medical disorders and social economic factors, with the end results showing that cases were more likely than controls to have a prior diagnosis of tinnitus (OR 1.779, 95% CI 1.582–2.001, p < 0.001). Through our investigation, we have ultimately detected a novel association between ED and tinnitus and urge physicians to be alert to the possibility of the development of ED in patients treated for tinnitus.
format	article
author	Yen-Fu Cheng Sudha Xirasagar Nai-Wen Kuo Shiu-Dong Chung Herng-Ching Lin
author_facet	Yen-Fu Cheng Sudha Xirasagar Nai-Wen Kuo Shiu-Dong Chung Herng-Ching Lin
author_sort	Yen-Fu Cheng
title	Association of erectile dysfunction with tinnitus: a nationwide population-based study
title_short	Association of erectile dysfunction with tinnitus: a nationwide population-based study
title_full	Association of erectile dysfunction with tinnitus: a nationwide population-based study
title_fullStr	Association of erectile dysfunction with tinnitus: a nationwide population-based study
title_full_unstemmed	Association of erectile dysfunction with tinnitus: a nationwide population-based study
title_sort	association of erectile dysfunction with tinnitus: a nationwide population-based study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/ea7e7a706cdf4a6f8eed0a308d601539
work_keys_str_mv	AT yenfucheng associationoferectiledysfunctionwithtinnitusanationwidepopulationbasedstudy AT sudhaxirasagar associationoferectiledysfunctionwithtinnitusanationwidepopulationbasedstudy AT naiwenkuo associationoferectiledysfunctionwithtinnitusanationwidepopulationbasedstudy AT shiudongchung associationoferectiledysfunctionwithtinnitusanationwidepopulationbasedstudy AT herngchinglin associationoferectiledysfunctionwithtinnitusanationwidepopulationbasedstudy
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Association of erectile dysfunction with tinnitus: a nationwide population-based study

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