lncRNA transcription induces meiotic recombination through chromatin remodelling in fission yeast
Senmatsu et al. show that transcription of long-noncoding RNAs (lncRNA) previously identified in the fission yeast fbp1 gene and found to induce chromatin opening, also activates meiotic recombination by inducing local chromatin remodeling at a meiotic recombination hotspot. This study furthers our...
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2021
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/ea8750ca570c4afb9db2fad8f016f469 |
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| Sumario: | Senmatsu et al. show that transcription of long-noncoding RNAs (lncRNA) previously identified in the fission yeast fbp1 gene and found to induce chromatin opening, also activates meiotic recombination by inducing local chromatin remodeling at a meiotic recombination hotspot. This study furthers our understanding of the connection between lncRNA transcription and DNA break activity in yeast meiosis. |
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