Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila

Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.

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Detalles Bibliográficos
Autores principales: Stéphanie Soulé, Lucille Mellottée, Abdelkrim Arab, Chongjian Chen, Jean-René Martin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/ea87f32d97ee43c0a80d64f05b4df325
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Descripción
Sumario:Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.