Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila

Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.

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Autores principales:	Stéphanie Soulé, Lucille Mellottée, Abdelkrim Arab, Chongjian Chen, Jean-René Martin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/ea87f32d97ee43c0a80d64f05b4df325
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id	oai:doaj.org-article:ea87f32d97ee43c0a80d64f05b4df325
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spelling	oai:doaj.org-article:ea87f32d97ee43c0a80d64f05b4df3252021-12-02T15:39:21ZJouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila10.1038/s41467-020-14784-12041-1723https://doaj.org/article/ea87f32d97ee43c0a80d64f05b4df3252020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14784-1https://doaj.org/toc/2041-1723Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.Stéphanie SouléLucille MellottéeAbdelkrim ArabChongjian ChenJean-René MartinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stéphanie Soulé Lucille Mellottée Abdelkrim Arab Chongjian Chen Jean-René Martin Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
description	Small non-coding RNAs contribute to the regulation of aging. Here the authors identify a small nucleolar RNA, the snoRNA jouvence, which extends the lifespan of fruit flies through its function in the gut, and is conserved in humans.
format	article
author	Stéphanie Soulé Lucille Mellottée Abdelkrim Arab Chongjian Chen Jean-René Martin
author_facet	Stéphanie Soulé Lucille Mellottée Abdelkrim Arab Chongjian Chen Jean-René Martin
author_sort	Stéphanie Soulé
title	Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
title_short	Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
title_full	Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
title_fullStr	Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
title_full_unstemmed	Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
title_sort	jouvence a small nucleolar rna required in the gut extends lifespan in drosophila
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/ea87f32d97ee43c0a80d64f05b4df325
work_keys_str_mv	AT stephaniesoule jouvenceasmallnucleolarrnarequiredinthegutextendslifespanindrosophila AT lucillemellottee jouvenceasmallnucleolarrnarequiredinthegutextendslifespanindrosophila AT abdelkrimarab jouvenceasmallnucleolarrnarequiredinthegutextendslifespanindrosophila AT chongjianchen jouvenceasmallnucleolarrnarequiredinthegutextendslifespanindrosophila AT jeanrenemartin jouvenceasmallnucleolarrnarequiredinthegutextendslifespanindrosophila
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Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila

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