Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Exposure to multiple pathogens is common in nature, yet interactions between the immune components targeting bacterial and viral pathogens during co-infection are poorly understood. Here the authors show that bacteria-derived LPS induces cytotoxic NK cells that suppress antiviral CD8 T cell response...

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Autores principales: Tobias Straub, Marina A. Freudenberg, Ulrike Schleicher, Christian Bogdan, Georg Gasteiger, Hanspeter Pircher
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/ea8d1ad39a4f4d37855579d39f274857
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