Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses

Action potentials induce synchronous and asynchronous release of neurotransmitters. Here, the authors show that the synchronous and asynchronous release sites are aligned with AMPARs and NMDARs, respectively, in mouse hippocampal synapses. This organization allows efficient activation of NMDARs.

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Autores principales:	Shuo Li, Sumana Raychaudhuri, Stephen Alexander Lee, Marisa M. Brockmann, Jing Wang, Grant Kusick, Christine Prater, Sarah Syed, Hanieh Falahati, Raul Ramos, Tomas M. Bartol, Eric Hosy, Shigeki Watanabe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/eaa1dbfabc834db792c456f47bdb3077
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spelling	oai:doaj.org-article:eaa1dbfabc834db792c456f47bdb30772021-12-02T10:48:09ZAsynchronous release sites align with NMDA receptors in mouse hippocampal synapses10.1038/s41467-021-21004-x2041-1723https://doaj.org/article/eaa1dbfabc834db792c456f47bdb30772021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21004-xhttps://doaj.org/toc/2041-1723Action potentials induce synchronous and asynchronous release of neurotransmitters. Here, the authors show that the synchronous and asynchronous release sites are aligned with AMPARs and NMDARs, respectively, in mouse hippocampal synapses. This organization allows efficient activation of NMDARs.Shuo LiSumana RaychaudhuriStephen Alexander LeeMarisa M. BrockmannJing WangGrant KusickChristine PraterSarah SyedHanieh FalahatiRaul RamosTomas M. BartolEric HosyShigeki WatanabeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shuo Li Sumana Raychaudhuri Stephen Alexander Lee Marisa M. Brockmann Jing Wang Grant Kusick Christine Prater Sarah Syed Hanieh Falahati Raul Ramos Tomas M. Bartol Eric Hosy Shigeki Watanabe Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
description	Action potentials induce synchronous and asynchronous release of neurotransmitters. Here, the authors show that the synchronous and asynchronous release sites are aligned with AMPARs and NMDARs, respectively, in mouse hippocampal synapses. This organization allows efficient activation of NMDARs.
format	article
author	Shuo Li Sumana Raychaudhuri Stephen Alexander Lee Marisa M. Brockmann Jing Wang Grant Kusick Christine Prater Sarah Syed Hanieh Falahati Raul Ramos Tomas M. Bartol Eric Hosy Shigeki Watanabe
author_facet	Shuo Li Sumana Raychaudhuri Stephen Alexander Lee Marisa M. Brockmann Jing Wang Grant Kusick Christine Prater Sarah Syed Hanieh Falahati Raul Ramos Tomas M. Bartol Eric Hosy Shigeki Watanabe
author_sort	Shuo Li
title	Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
title_short	Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
title_full	Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
title_fullStr	Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
title_full_unstemmed	Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses
title_sort	asynchronous release sites align with nmda receptors in mouse hippocampal synapses
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eaa1dbfabc834db792c456f47bdb3077
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Asynchronous release sites align with NMDA receptors in mouse hippocampal synapses

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