Systems biology drug screening identifies statins as enhancers of current therapies in chronic lymphocytic leukemia
Abstract Chronic lymphocytic leukemia (CLL) is a B lymphoid malignancy highly dependent on the microenvironment. Despite new targeted therapies such as ibrutinib and venetoclax, disease progression and relapse remain an issue. CLL cell interactions with the supportive tissue microenvironment play a...
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Autores principales: | , , , , , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2020
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Acceso en línea: | https://doaj.org/article/eaa533646552409fbba838dfbdc5b89d |
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