Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka

Junpei Yamashita et al. use a medaka model to evaluate how neurons in the preoptic area that express the neuropeptides, PACAP and VIP, regulate pituitary hormones. Their results suggest that estrogen helps maintain sex-dependent activity of these neurons, leading to sexually dimorphic pituitary horm...

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Autores principales: Junpei Yamashita, Yuji Nishiike, Thomas Fleming, Daichi Kayo, Kataaki Okubo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/eaaaa8b92fae423ca9e9384fa05ac503
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spelling oai:doaj.org-article:eaaaa8b92fae423ca9e9384fa05ac5032021-12-02T15:07:46ZEstrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka10.1038/s42003-021-02476-52399-3642https://doaj.org/article/eaaaa8b92fae423ca9e9384fa05ac5032021-08-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02476-5https://doaj.org/toc/2399-3642Junpei Yamashita et al. use a medaka model to evaluate how neurons in the preoptic area that express the neuropeptides, PACAP and VIP, regulate pituitary hormones. Their results suggest that estrogen helps maintain sex-dependent activity of these neurons, leading to sexually dimorphic pituitary hormone production.Junpei YamashitaYuji NishiikeThomas FlemingDaichi KayoKataaki OkuboNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Junpei Yamashita
Yuji Nishiike
Thomas Fleming
Daichi Kayo
Kataaki Okubo
Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
description Junpei Yamashita et al. use a medaka model to evaluate how neurons in the preoptic area that express the neuropeptides, PACAP and VIP, regulate pituitary hormones. Their results suggest that estrogen helps maintain sex-dependent activity of these neurons, leading to sexually dimorphic pituitary hormone production.
format article
author Junpei Yamashita
Yuji Nishiike
Thomas Fleming
Daichi Kayo
Kataaki Okubo
author_facet Junpei Yamashita
Yuji Nishiike
Thomas Fleming
Daichi Kayo
Kataaki Okubo
author_sort Junpei Yamashita
title Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
title_short Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
title_full Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
title_fullStr Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
title_full_unstemmed Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
title_sort estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/eaaaa8b92fae423ca9e9384fa05ac503
work_keys_str_mv AT junpeiyamashita estrogenmediatessexdifferencesinpreopticneuropeptideandpituitaryhormoneproductioninmedaka
AT yujinishiike estrogenmediatessexdifferencesinpreopticneuropeptideandpituitaryhormoneproductioninmedaka
AT thomasfleming estrogenmediatessexdifferencesinpreopticneuropeptideandpituitaryhormoneproductioninmedaka
AT daichikayo estrogenmediatessexdifferencesinpreopticneuropeptideandpituitaryhormoneproductioninmedaka
AT kataakiokubo estrogenmediatessexdifferencesinpreopticneuropeptideandpituitaryhormoneproductioninmedaka
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