The role of the P2X₇ receptor in infectious diseases.
ATP is an extracellular signal for the immune system, particularly during an inflammatory response. It is sensed by the P2X₇ receptor, the expression of which is upregulated by pro-inflammatory cytokines. Activation of the P2X₇ receptor opens a cation-specific channel that alters the ionic environme...
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Autores principales: | Catherine M Miller, Nicola R Boulter, Stephen J Fuller, Alana M Zakrzewski, Michael P Lees, Bernadette M Saunders, James S Wiley, Nicholas C Smith |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/eaae2f5f8dfd4171bed244a273cb96bf |
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