Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

Cancer-associated fibroblasts induce metalloprotease-independent cancer cell invasion of the basement membrane

Stromal cells play various roles in tumor establishment and metastasis. Here the authors, using an ex-vivo model, show that cancer-associated fibroblasts facilitate colon cancer cells invasion in a matrix metalloproteinase-independent manner, likely by pulling and stretching the basement membrane to...

Full description

Saved in:
Bibliographic Details
Main Authors: Alexandros Glentis, Philipp Oertle, Pascale Mariani, Aleksandra Chikina, Fatima El Marjou, Youmna Attieh, Francois Zaccarini, Marick Lae, Damarys Loew, Florent Dingli, Philemon Sirven, Marie Schoumacher, Basile G. Gurchenkov, Marija Plodinec, Danijela Matic Vignjevic
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Science
Q
Online Access:https://doaj.org/article/eabac0b9dbc84f519ed0cf211931944c
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items