Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality

Aim: to establish a link between the level of folic acid, vitamin D and iodine consumption, and infant and perinatal mortality, morbidity of childhood tuberculosis in the Irkutsk region. Consumption of folate in the form of a single-agent preparation increased 3 times in 5 years. Consumption of foli...

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Autores principales:	L. A. Reshetnik, T. A. Spasich, T. V. Boyko, M. V. Grigorieva, I. Y. Kozlovskaya
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2017
Materias:	infant mortality folic acid vitamin d iodine iodine endemia Science Q
Acceso en línea:	https://doaj.org/article/eabb195616fe4e178b910496f5d8f0ab
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spelling	oai:doaj.org-article:eabb195616fe4e178b910496f5d8f0ab2021-11-23T06:14:38ZCorrection of micronutrient status of the Irkutsk region population as a means of lowering infant mortality2541-94202587-959610.12737/article_5a3a0d9708a6a1.90095685https://doaj.org/article/eabb195616fe4e178b910496f5d8f0ab2017-09-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/504https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Aim: to establish a link between the level of folic acid, vitamin D and iodine consumption, and infant and perinatal mortality, morbidity of childhood tuberculosis in the Irkutsk region. Consumption of folate in the form of a single-agent preparation increased 3 times in 5 years. Consumption of folic acid in women at the stage of preconception and pregnancy affected the reduction of perinatal (R = -0.9; p = 0.016) and infant (R = -0.89; p = 0.04) mortality, including neonatal (R = -0.89; p = 0.039). Preventive supplementation of vitamin D of people in the region over the past 5years has increased by 70 %, and infant mortality fell by 35.5 %. Infant (R = -0.94; p = 0.01) and especially post-neonatal (R = -0.97; p = 0.004) mortality are controllable and depend on the prevention of hypovitaminosis D. The understanding of the role of vitamin D in triggering the synthesis of the antimicrobial peptide cathelicidin opens prospects for using it as a medicine for prevention and treatment of childhood tuberculosis. The incidence of pediatric tuberculosis in the region during this period decreased by 46 % (R = -0.95; p = 0.01). Correction of iodine deficiency in pregnant women and children caused the reduction of perinatal (R = -0.99; p = 0.07), early neonatal (R = -0.99; p = 0.05), neonatal (R = -0.98; p = 0.06) and post-neonatal (R = -0.99; p = 0.002) infant mortality.L. A. ReshetnikT. A. SpasichT. V. BoykoM. V. GrigorievaI. Y. KozlovskayaScientific Сentre for Family Health and Human Reproduction Problemsarticleinfant mortalityfolic acidvitamin diodineiodine endemiaScienceQRUActa Biomedica Scientifica, Vol 2, Iss 5(2), Pp 37-42 (2017)
institution	DOAJ
collection	DOAJ
language	RU
topic	infant mortality folic acid vitamin d iodine iodine endemia Science Q
spellingShingle	infant mortality folic acid vitamin d iodine iodine endemia Science Q L. A. Reshetnik T. A. Spasich T. V. Boyko M. V. Grigorieva I. Y. Kozlovskaya Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
description	Aim: to establish a link between the level of folic acid, vitamin D and iodine consumption, and infant and perinatal mortality, morbidity of childhood tuberculosis in the Irkutsk region. Consumption of folate in the form of a single-agent preparation increased 3 times in 5 years. Consumption of folic acid in women at the stage of preconception and pregnancy affected the reduction of perinatal (R = -0.9; p = 0.016) and infant (R = -0.89; p = 0.04) mortality, including neonatal (R = -0.89; p = 0.039). Preventive supplementation of vitamin D of people in the region over the past 5years has increased by 70 %, and infant mortality fell by 35.5 %. Infant (R = -0.94; p = 0.01) and especially post-neonatal (R = -0.97; p = 0.004) mortality are controllable and depend on the prevention of hypovitaminosis D. The understanding of the role of vitamin D in triggering the synthesis of the antimicrobial peptide cathelicidin opens prospects for using it as a medicine for prevention and treatment of childhood tuberculosis. The incidence of pediatric tuberculosis in the region during this period decreased by 46 % (R = -0.95; p = 0.01). Correction of iodine deficiency in pregnant women and children caused the reduction of perinatal (R = -0.99; p = 0.07), early neonatal (R = -0.99; p = 0.05), neonatal (R = -0.98; p = 0.06) and post-neonatal (R = -0.99; p = 0.002) infant mortality.
format	article
author	L. A. Reshetnik T. A. Spasich T. V. Boyko M. V. Grigorieva I. Y. Kozlovskaya
author_facet	L. A. Reshetnik T. A. Spasich T. V. Boyko M. V. Grigorieva I. Y. Kozlovskaya
author_sort	L. A. Reshetnik
title	Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
title_short	Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
title_full	Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
title_fullStr	Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
title_full_unstemmed	Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality
title_sort	correction of micronutrient status of the irkutsk region population as a means of lowering infant mortality
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2017
url	https://doaj.org/article/eabb195616fe4e178b910496f5d8f0ab
work_keys_str_mv	AT lareshetnik correctionofmicronutrientstatusoftheirkutskregionpopulationasameansofloweringinfantmortality AT taspasich correctionofmicronutrientstatusoftheirkutskregionpopulationasameansofloweringinfantmortality AT tvboyko correctionofmicronutrientstatusoftheirkutskregionpopulationasameansofloweringinfantmortality AT mvgrigorieva correctionofmicronutrientstatusoftheirkutskregionpopulationasameansofloweringinfantmortality AT iykozlovskaya correctionofmicronutrientstatusoftheirkutskregionpopulationasameansofloweringinfantmortality
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Correction of micronutrient status of the Irkutsk region population as a means of lowering infant mortality

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