Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App NL-G-F , App NL-F , and wild type mice

Integrated analysis of behavioral, epigenetic, and gut microbiome analyses in App NL-G-F , App NL-F , and wild type mice

Abstract Epigenetic mechanisms occurring in the brain as well as alterations in the gut microbiome composition might contribute to Alzheimer’s disease (AD). Human amyloid precursor protein knock-in (KI) mice contain the Swedish and Iberian mutations (App NL-F ) or those two and also the Arctic mutat...

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Main Authors: Payel Kundu, Eileen Ruth S. Torres, Keaton Stagaman, Kristin Kasschau, Mariam Okhovat, Sarah Holden, Samantha Ward, Kimberly A. Nevonen, Brett A. Davis, Takashi Saito, Takaomi C. Saido, Lucia Carbone, Thomas J. Sharpton, Jacob Raber
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/eabb5988f5e94c96a3c3a0cc1f5de7bc
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