Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles
Hamdi Trabelsi, Inès Azzouz, Mohsen Sakly, Hafedh Abdelmelek Laboratory of Physiologie Intégrée, Faculty of Sciences of Bizerte, Carthage University, Tunisia Abstract: The purpose was to study the toxicity of cadmium (Cd) and to explore its potential to g...
Guardado en:
| Autores principales: | , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2013
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/eabcfe276ba54a0598dd6c3383ffc91a |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:eabcfe276ba54a0598dd6c3383ffc91a |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:eabcfe276ba54a0598dd6c3383ffc91a2021-12-02T02:28:09ZSubacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles1176-91141178-2013https://doaj.org/article/eabcfe276ba54a0598dd6c3383ffc91a2013-03-01T00:00:00Zhttp://www.dovepress.com/subacute-toxicity-of-cadmium-on-hepatocytes-and-nephrocytes-in-the-rat-a12465https://doaj.org/toc/1176-9114https://doaj.org/toc/1178-2013Hamdi Trabelsi, Inès Azzouz, Mohsen Sakly, Hafedh Abdelmelek Laboratory of Physiologie Intégrée, Faculty of Sciences of Bizerte, Carthage University, Tunisia Abstract: The purpose was to study the toxicity of cadmium (Cd) and to explore its potential to generate nanoparticles during detoxification. In order to demonstrate this, in vivo fluorescence imaging, X-ray diffraction, and flow cytometry were performed. The in vivo imaging showed a fluorescence signal after Cd treatment (CdCl2, 1.50 mg/Kg, intraperitoneally). By contrast, the control-rat fluorescence was negative. The fluorescence was divided into three colors, red, yellow, and green, and probably indicates the presence of quantum dots. X-ray diffraction results revealed the presence of Cd sulfide (CdS) and/or Cd selenide (CdSe) nanoparticles following Cd injection in the liver (6.52 nm) and kidneys (56.30 nm). Interestingly, flow cytometry revealed a heterogeneous size distribution and a homogeneous granularity of synthesized nanoparticles. Using the green fluorescence channel and the red fluorescence channel, a narrow green emission spectrum and a broad red emission spectrum were detected, respectively, by cytometric analysis. Keywords: XRD, in vivo imaging, flow cytometry, quantum dots, cadmium sulfide, cadmium selenideTrabelsi HAzzouz ISakly MAbdelmelek HDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2013, Iss default, Pp 1121-1128 (2013) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Medicine (General) R5-920 |
| spellingShingle |
Medicine (General) R5-920 Trabelsi H Azzouz I Sakly M Abdelmelek H Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| description |
Hamdi Trabelsi, Inès Azzouz, Mohsen Sakly, Hafedh Abdelmelek Laboratory of Physiologie Intégrée, Faculty of Sciences of Bizerte, Carthage University, Tunisia Abstract: The purpose was to study the toxicity of cadmium (Cd) and to explore its potential to generate nanoparticles during detoxification. In order to demonstrate this, in vivo fluorescence imaging, X-ray diffraction, and flow cytometry were performed. The in vivo imaging showed a fluorescence signal after Cd treatment (CdCl2, 1.50 mg/Kg, intraperitoneally). By contrast, the control-rat fluorescence was negative. The fluorescence was divided into three colors, red, yellow, and green, and probably indicates the presence of quantum dots. X-ray diffraction results revealed the presence of Cd sulfide (CdS) and/or Cd selenide (CdSe) nanoparticles following Cd injection in the liver (6.52 nm) and kidneys (56.30 nm). Interestingly, flow cytometry revealed a heterogeneous size distribution and a homogeneous granularity of synthesized nanoparticles. Using the green fluorescence channel and the red fluorescence channel, a narrow green emission spectrum and a broad red emission spectrum were detected, respectively, by cytometric analysis. Keywords: XRD, in vivo imaging, flow cytometry, quantum dots, cadmium sulfide, cadmium selenide |
| format |
article |
| author |
Trabelsi H Azzouz I Sakly M Abdelmelek H |
| author_facet |
Trabelsi H Azzouz I Sakly M Abdelmelek H |
| author_sort |
Trabelsi H |
| title |
Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| title_short |
Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| title_full |
Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| title_fullStr |
Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| title_full_unstemmed |
Subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| title_sort |
subacute toxicity of cadmium on hepatocytes and nephrocytes in the rat could be considered as a green biosynthesis of nanoparticles |
| publisher |
Dove Medical Press |
| publishDate |
2013 |
| url |
https://doaj.org/article/eabcfe276ba54a0598dd6c3383ffc91a |
| work_keys_str_mv |
AT trabelsih subacutetoxicityofcadmiumonhepatocytesandnephrocytesintheratcouldbeconsideredasagreenbiosynthesisofnanoparticles AT azzouzi subacutetoxicityofcadmiumonhepatocytesandnephrocytesintheratcouldbeconsideredasagreenbiosynthesisofnanoparticles AT saklym subacutetoxicityofcadmiumonhepatocytesandnephrocytesintheratcouldbeconsideredasagreenbiosynthesisofnanoparticles AT abdelmelekh subacutetoxicityofcadmiumonhepatocytesandnephrocytesintheratcouldbeconsideredasagreenbiosynthesisofnanoparticles |
| _version_ |
1718402502077972480 |