Novel chikungunya vaccine candidate with an IRES-based attenuation and host range alteration mechanism.
Chikungunya virus (CHIKV) is a reemerging mosquito-borne pathogen that has recently caused devastating urban epidemics of severe and sometimes chronic arthralgia. As with most other mosquito-borne viral diseases, control relies on reducing mosquito populations and their contact with people, which ha...
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Autores principales: | Kenneth Plante, Eryu Wang, Charalambos D Partidos, James Weger, Rodion Gorchakov, Konstantin Tsetsarkin, Erin M Borland, Ann M Powers, Robert Seymour, Dan T Stinchcomb, Jorge E Osorio, Ilya Frolov, Scott C Weaver |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2011
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Materias: | |
Acceso en línea: | https://doaj.org/article/eac4c566b2654d0ab41db960f375abb0 |
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