Inference and analysis of cell-cell communication using CellChat

Single-cell methods record molecule expressions of cells in a given tissue, but understanding interactions between cells remains challenging. Here the authors show by applying systems biology and machine learning approaches that they can infer and analyze cell-cell communication networks in an easil...

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Auteurs principaux: Suoqin Jin, Christian F. Guerrero-Juarez, Lihua Zhang, Ivan Chang, Raul Ramos, Chen-Hsiang Kuan, Peggy Myung, Maksim V. Plikus, Qing Nie
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/eac776c8aeed43009b282c2dd2c6db3b
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spelling oai:doaj.org-article:eac776c8aeed43009b282c2dd2c6db3b2021-12-02T14:21:27ZInference and analysis of cell-cell communication using CellChat10.1038/s41467-021-21246-92041-1723https://doaj.org/article/eac776c8aeed43009b282c2dd2c6db3b2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21246-9https://doaj.org/toc/2041-1723Single-cell methods record molecule expressions of cells in a given tissue, but understanding interactions between cells remains challenging. Here the authors show by applying systems biology and machine learning approaches that they can infer and analyze cell-cell communication networks in an easily interpretable way.Suoqin JinChristian F. Guerrero-JuarezLihua ZhangIvan ChangRaul RamosChen-Hsiang KuanPeggy MyungMaksim V. PlikusQing NieNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Suoqin Jin
Christian F. Guerrero-Juarez
Lihua Zhang
Ivan Chang
Raul Ramos
Chen-Hsiang Kuan
Peggy Myung
Maksim V. Plikus
Qing Nie
Inference and analysis of cell-cell communication using CellChat
description Single-cell methods record molecule expressions of cells in a given tissue, but understanding interactions between cells remains challenging. Here the authors show by applying systems biology and machine learning approaches that they can infer and analyze cell-cell communication networks in an easily interpretable way.
format article
author Suoqin Jin
Christian F. Guerrero-Juarez
Lihua Zhang
Ivan Chang
Raul Ramos
Chen-Hsiang Kuan
Peggy Myung
Maksim V. Plikus
Qing Nie
author_facet Suoqin Jin
Christian F. Guerrero-Juarez
Lihua Zhang
Ivan Chang
Raul Ramos
Chen-Hsiang Kuan
Peggy Myung
Maksim V. Plikus
Qing Nie
author_sort Suoqin Jin
title Inference and analysis of cell-cell communication using CellChat
title_short Inference and analysis of cell-cell communication using CellChat
title_full Inference and analysis of cell-cell communication using CellChat
title_fullStr Inference and analysis of cell-cell communication using CellChat
title_full_unstemmed Inference and analysis of cell-cell communication using CellChat
title_sort inference and analysis of cell-cell communication using cellchat
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/eac776c8aeed43009b282c2dd2c6db3b
work_keys_str_mv AT suoqinjin inferenceandanalysisofcellcellcommunicationusingcellchat
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AT ivanchang inferenceandanalysisofcellcellcommunicationusingcellchat
AT raulramos inferenceandanalysisofcellcellcommunicationusingcellchat
AT chenhsiangkuan inferenceandanalysisofcellcellcommunicationusingcellchat
AT peggymyung inferenceandanalysisofcellcellcommunicationusingcellchat
AT maksimvplikus inferenceandanalysisofcellcellcommunicationusingcellchat
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