<named-content content-type="genus-species">Clostridium difficile</named-content> Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule

<named-content content-type="genus-species">Clostridium difficile</named-content> Modulates the Gut Microbiota by Inducing the Production of Indole, an Interkingdom Signaling and Antimicrobial Molecule

ABSTRACT Clostridium (Clostridioides) difficile infection (CDI) is associated with dysbiosis. C. difficile has a characteristic propensity to persist and recur 1 to 4 weeks after treatment, but the mechanism is unknown. We hypothesized that C. difficile may persist by manipulating the intestinal mic...

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Autores principales: Charles Darkoh, Kimberly Plants-Paris, Dayna Bishoff, Herbert L. DuPont
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
C. difficile
indole
C. difficile infection
indole production
gut microbiota
tryptophan biosynthesis
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/eacde341eda64ae6a7626bfc7a35090b
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