Balanced cholinergic modulation of spinal locomotor circuits via M2 and M3 muscarinic receptors
Abstract Neuromodulation ensures that neural circuits produce output that is flexible whilst remaining within an optimal operational range. The neuromodulator acetylcholine is released during locomotion to regulate spinal motor circuits. However, the range of receptors and downstream mechanisms by w...
Guardado en:
Autores principales: | Filipe Nascimento, Lennart R. B. Spindler, Gareth B. Miles |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/ead154b865504c6eb379cbf73316014b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
All muscarinic acetylcholine receptors (M1-M5) are expressed in murine brain microvascular endothelium
por: Beatrice Mihaela Radu, et al.
Publicado: (2017) -
Structural determinants at the M2 muscarinic receptor modulate the RGS4-GIRK response to pilocarpine by impairment of the receptor voltage sensitivity
por: I-Shan Chen, et al.
Publicado: (2017) -
Vibrational spectroscopy analysis of ligand efficacy in human M2 muscarinic acetylcholine receptor (M2R)
por: Kota Katayama, et al.
Publicado: (2021) -
The M1 muscarinic acetylcholine receptor subtype is important for retinal neuron survival in aging mice
por: Panagiotis Laspas, et al.
Publicado: (2019) -
Potential Role for Combined Subtype-Selective Targeting of M1 and M3 Muscarinic Receptors in Gastrointestinal and Liver Diseases
por: Mazen Tolaymat, et al.
Publicado: (2021)