Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion

Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion

Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion fro...

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Autores principales: Irene Cimino, Filippo Casoni, Xinhuai Liu, Andrea Messina, Jyoti Parkash, Soazik P. Jamin, Sophie Catteau-Jonard, Francis Collier, Marc Baroncini, Didier Dewailly, Pascal Pigny, Mel Prescott, Rebecca Campbell, Allan E. Herbison, Vincent Prevot, Paolo Giacobini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Science
Q
Acceso en línea:https://doaj.org/article/ead931edf8814ed5833fefa26664dd12
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Sumario:Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion from the pituitary gland.

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