Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion

Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion fro...

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Autores principales: Irene Cimino, Filippo Casoni, Xinhuai Liu, Andrea Messina, Jyoti Parkash, Soazik P. Jamin, Sophie Catteau-Jonard, Francis Collier, Marc Baroncini, Didier Dewailly, Pascal Pigny, Mel Prescott, Rebecca Campbell, Allan E. Herbison, Vincent Prevot, Paolo Giacobini
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/ead931edf8814ed5833fefa26664dd12
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spelling oai:doaj.org-article:ead931edf8814ed5833fefa26664dd122021-12-02T15:35:44ZNovel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion10.1038/ncomms100552041-1723https://doaj.org/article/ead931edf8814ed5833fefa26664dd122016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10055https://doaj.org/toc/2041-1723Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion from the pituitary gland.Irene CiminoFilippo CasoniXinhuai LiuAndrea MessinaJyoti ParkashSoazik P. JaminSophie Catteau-JonardFrancis CollierMarc BaronciniDidier DewaillyPascal PignyMel PrescottRebecca CampbellAllan E. HerbisonVincent PrevotPaolo GiacobiniNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Irene Cimino
Filippo Casoni
Xinhuai Liu
Andrea Messina
Jyoti Parkash
Soazik P. Jamin
Sophie Catteau-Jonard
Francis Collier
Marc Baroncini
Didier Dewailly
Pascal Pigny
Mel Prescott
Rebecca Campbell
Allan E. Herbison
Vincent Prevot
Paolo Giacobini
Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
description Anti-Müllerian hormone (AMH) plays a role in sexual differentiation and gonadal function, but extra-gonadal effects of AMH are not known. Here Cimino et al. show that AMH activates a subset of gonadotrophin-releasing hormone (GnRH)-releasing neurons, contributing to luteinizing hormone secretion from the pituitary gland.
format article
author Irene Cimino
Filippo Casoni
Xinhuai Liu
Andrea Messina
Jyoti Parkash
Soazik P. Jamin
Sophie Catteau-Jonard
Francis Collier
Marc Baroncini
Didier Dewailly
Pascal Pigny
Mel Prescott
Rebecca Campbell
Allan E. Herbison
Vincent Prevot
Paolo Giacobini
author_facet Irene Cimino
Filippo Casoni
Xinhuai Liu
Andrea Messina
Jyoti Parkash
Soazik P. Jamin
Sophie Catteau-Jonard
Francis Collier
Marc Baroncini
Didier Dewailly
Pascal Pigny
Mel Prescott
Rebecca Campbell
Allan E. Herbison
Vincent Prevot
Paolo Giacobini
author_sort Irene Cimino
title Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
title_short Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
title_full Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
title_fullStr Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
title_full_unstemmed Novel role for anti-Müllerian hormone in the regulation of GnRH neuron excitability and hormone secretion
title_sort novel role for anti-müllerian hormone in the regulation of gnrh neuron excitability and hormone secretion
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/ead931edf8814ed5833fefa26664dd12
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