Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics

Marc Van Goethem et al. combine short- and long-read sequencing from biocrust samples to report nearly 3,000 biosynthetic gene clusters (BGCs) encoding microbial secondary metabolites. Their results demonstrate the advantage of integrated metatranscriptomic and long-read metagenomic sequencing in an...

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Autores principales:	Marc W. Van Goethem, Andrew R. Osborn, Benjamin P. Bowen, Peter F. Andeer, Tami L. Swenson, Alicia Clum, Robert Riley, Guifen He, Maxim Koriabine, Laura Sandor, Mi Yan, Chris G. Daum, Yuko Yoshinaga, Thulani P. Makhalanyane, Ferran Garcia-Pichel, Axel Visel, Len A. Pennacchio, Ronan C. O’Malley, Trent R. Northen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/eae224afa2b747cc9f684dcc3d7db239
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spelling	oai:doaj.org-article:eae224afa2b747cc9f684dcc3d7db2392021-11-21T12:08:28ZLong-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics10.1038/s42003-021-02809-42399-3642https://doaj.org/article/eae224afa2b747cc9f684dcc3d7db2392021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02809-4https://doaj.org/toc/2399-3642Marc Van Goethem et al. combine short- and long-read sequencing from biocrust samples to report nearly 3,000 biosynthetic gene clusters (BGCs) encoding microbial secondary metabolites. Their results demonstrate the advantage of integrated metatranscriptomic and long-read metagenomic sequencing in analyzing BGCs and provides insight into the role of secondary metabolites in maintaining phylogenetic niches in biocrusts.Marc W. Van GoethemAndrew R. OsbornBenjamin P. BowenPeter F. AndeerTami L. SwensonAlicia ClumRobert RileyGuifen HeMaxim KoriabineLaura SandorMi YanChris G. DaumYuko YoshinagaThulani P. MakhalanyaneFerran Garcia-PichelAxel ViselLen A. PennacchioRonan C. O’MalleyTrent R. NorthenNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Marc W. Van Goethem Andrew R. Osborn Benjamin P. Bowen Peter F. Andeer Tami L. Swenson Alicia Clum Robert Riley Guifen He Maxim Koriabine Laura Sandor Mi Yan Chris G. Daum Yuko Yoshinaga Thulani P. Makhalanyane Ferran Garcia-Pichel Axel Visel Len A. Pennacchio Ronan C. O’Malley Trent R. Northen Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
description	Marc Van Goethem et al. combine short- and long-read sequencing from biocrust samples to report nearly 3,000 biosynthetic gene clusters (BGCs) encoding microbial secondary metabolites. Their results demonstrate the advantage of integrated metatranscriptomic and long-read metagenomic sequencing in analyzing BGCs and provides insight into the role of secondary metabolites in maintaining phylogenetic niches in biocrusts.
format	article
author	Marc W. Van Goethem Andrew R. Osborn Benjamin P. Bowen Peter F. Andeer Tami L. Swenson Alicia Clum Robert Riley Guifen He Maxim Koriabine Laura Sandor Mi Yan Chris G. Daum Yuko Yoshinaga Thulani P. Makhalanyane Ferran Garcia-Pichel Axel Visel Len A. Pennacchio Ronan C. O’Malley Trent R. Northen
author_facet	Marc W. Van Goethem Andrew R. Osborn Benjamin P. Bowen Peter F. Andeer Tami L. Swenson Alicia Clum Robert Riley Guifen He Maxim Koriabine Laura Sandor Mi Yan Chris G. Daum Yuko Yoshinaga Thulani P. Makhalanyane Ferran Garcia-Pichel Axel Visel Len A. Pennacchio Ronan C. O’Malley Trent R. Northen
author_sort	Marc W. Van Goethem
title	Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
title_short	Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
title_full	Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
title_fullStr	Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
title_full_unstemmed	Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
title_sort	long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/eae224afa2b747cc9f684dcc3d7db239
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Long-read metagenomics of soil communities reveals phylum-specific secondary metabolite dynamics

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