Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani
Abstract We investigate the role of methionine aminopeptidase 2 (MAP2) in miltefosine induced programmed cell death (PCD) in promastigote form of L. donovani. We report that TNP-470, an inhibitor of MAP2, inhibits programmed cell death in miltefosine treated promastigotes. It inhibits the biochemica...
Saved in:
Main Authors: | Ritesh Kumar, Kartikeya Tiwari, Vikash Kumar Dubey |
---|---|
Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2017
|
Subjects: | |
Online Access: | https://doaj.org/article/eae507987eb945d5a3481885f159af9c |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
HO-3867 Induces ROS-Dependent Stress Response and Apoptotic Cell Death in Leishmania donovani
by: Amrita Das, et al.
Published: (2021) -
Inhibition of the methionine aminopeptidase 2 enzyme for the treatment of obesity
by: Joharapurkar AA, et al.
Published: (2014) -
Leishmania donovani triose phosphate isomerase: a potential vaccine target against visceral leishmaniasis.
by: Pramod K Kushawaha, et al.
Published: (2012) -
Distinct microbiome profiles and biofilms in Leishmania donovani-driven cutaneous leishmaniasis wounds
by: T. D. Jayasena Kaluarachchi, et al.
Published: (2021) -
Development of Quantitative Rapid Isothermal Amplification Assay for <i>Leishmania donovani</i>
by: Md Anik Ashfaq Khan, et al.
Published: (2021)