Methionine aminopeptidase 2 is a key regulator of apoptotic like cell death in Leishmania donovani

Abstract We investigate the role of methionine aminopeptidase 2 (MAP2) in miltefosine induced programmed cell death (PCD) in promastigote form of L. donovani. We report that TNP-470, an inhibitor of MAP2, inhibits programmed cell death in miltefosine treated promastigotes. It inhibits the biochemica...

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Bibliographic Details
Main Authors: Ritesh Kumar, Kartikeya Tiwari, Vikash Kumar Dubey
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
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Online Access:https://doaj.org/article/eae507987eb945d5a3481885f159af9c
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